PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19154774-3	2009	We show that in addition to GABA(B), GISP exerts a more general role to increase the steady-state levels of several neurotransmitter receptors.	gamma-Aminobutyric Acid	28-32	regenerating family member 4	Homo sapiens	37-41	
18643869-2	2008	We originally isolated GISP as an interacting partner for the GABA(B) receptor subunit GABA(B1).	gamma-Aminobutyric Acid	62-66	regenerating family member 4	Homo sapiens	23-27	
18643869-6	2008	GISP also inhibits TSG101-dependent GABA(B2) down-regulation in human embryonic kidney 293 cells whereas over-expression of a mutant GISP lacking the TSG101 binding domain has no effect on GABA(B2) degradation.	gamma-Aminobutyric Acid	36-40	regenerating family member 4	Homo sapiens	0-4	
17241134-3	2007	We report the identification and characterization of a novel 130-kDa protein, GPCR interacting scaffolding protein (GISP), that interacts directly with the GABA(B1) subunit via a coiled-coil domain.	gamma-Aminobutyric Acid	156-160	regenerating family member 4	Homo sapiens	78-114	
17241134-3	2007	We report the identification and characterization of a novel 130-kDa protein, GPCR interacting scaffolding protein (GISP), that interacts directly with the GABA(B1) subunit via a coiled-coil domain.	gamma-Aminobutyric Acid	156-160	regenerating family member 4	Homo sapiens	116-120	
17241134-5	2007	In cultured hippocampal neurons, GISP displays a punctate dendritic distribution and has an overlapping localization with GABA(B)Rs.	gamma-Aminobutyric Acid	122-126	regenerating family member 4	Homo sapiens	33-37	
17241134-6	2007	When co-expressed with GABA(B)Rs in human embryonic kidney cells, GISP promotes GABA(B)R surface expression and enhances both baclofen-evoked extracellular signal-regulated kinase (ERK) phosphorylation and G-protein inwardly rectifying potassium channel (GIRK) currents.	gamma-Aminobutyric Acid	23-27	regenerating family member 4	Homo sapiens	66-70	
17241134-6	2007	When co-expressed with GABA(B)Rs in human embryonic kidney cells, GISP promotes GABA(B)R surface expression and enhances both baclofen-evoked extracellular signal-regulated kinase (ERK) phosphorylation and G-protein inwardly rectifying potassium channel (GIRK) currents.	gamma-Aminobutyric Acid	80-84	regenerating family member 4	Homo sapiens	66-70	
17241134-7	2007	These results suggest that GISP is involved in the forward trafficking and stabilization of functional GABA(B)Rs.	gamma-Aminobutyric Acid	103-107	regenerating family member 4	Homo sapiens	27-31