PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29562624-0	2018	GABA and GABA-Alanine from the Red Microalgae Rhodosorus marinus Exhibit a Significant Neuro-Soothing Activity through Inhibition of Neuro-Inflammation Mediators and Positive Regulation of TRPV1-Related Skin Sensitization.	gamma-Aminobutyric Acid	0-4	transient receptor potential cation channel subfamily V member 1	Homo sapiens	189-194	
29562624-10	2018	Two active molecules, namely, gamma-aminobutyric acid (GABA) and its structural derivative GABA-alanine, demonstrated a strong capacity to positively regulate skin sensitization mechanisms related to the TRPV1 receptors under PMA-induced inflammatory conditions, therefore providing interesting perspectives for the treatment of sensitive skins, atopia, dermatitis, or psoriasis.	gamma-Aminobutyric Acid	30-53	transient receptor potential cation channel subfamily V member 1	Homo sapiens	204-209	
29562624-10	2018	Two active molecules, namely, gamma-aminobutyric acid (GABA) and its structural derivative GABA-alanine, demonstrated a strong capacity to positively regulate skin sensitization mechanisms related to the TRPV1 receptors under PMA-induced inflammatory conditions, therefore providing interesting perspectives for the treatment of sensitive skins, atopia, dermatitis, or psoriasis.	gamma-Aminobutyric Acid	55-59	transient receptor potential cation channel subfamily V member 1	Homo sapiens	204-209	
22936245-7	2013	In addition, its co-localization with glutamate and gamma-aminobutyric acid (GABA) indicated that TRPV1 was distributed on both glutamatergic and GABAergic neurons.	gamma-Aminobutyric Acid	52-75	transient receptor potential cation channel subfamily V member 1	Homo sapiens	98-103	
25679765-4	2015	We find that the endogenous GABAB agonist, GABA, is released from nociceptive nerve terminals, suggesting an autocrine feedback mechanism limiting TRPV1 sensitization.	gamma-Aminobutyric Acid	28-32	transient receptor potential cation channel subfamily V member 1	Homo sapiens	147-152	
22936245-7	2013	In addition, its co-localization with glutamate and gamma-aminobutyric acid (GABA) indicated that TRPV1 was distributed on both glutamatergic and GABAergic neurons.	gamma-Aminobutyric Acid	77-81	transient receptor potential cation channel subfamily V member 1	Homo sapiens	98-103	
21734101-4	2011	This study tested whether presynaptic gamma-aminobutyric acid (GABA)(B) receptors inhibit both the evoked and TRPV1-operated release mechanisms on second-order ST nucleus neurons.	gamma-Aminobutyric Acid	63-67	transient receptor potential cation channel subfamily V member 1	Homo sapiens	110-115	
21734101-7	2011	The GABA(B) agonist baclofen inhibited the amplitude of ST-EPSCs from both TRPV1+ and TRPV1- afferents with a similar EC(50) (~1.2 muM).	gamma-Aminobutyric Acid	4-8	transient receptor potential cation channel subfamily V member 1	Homo sapiens	75-80	
21734101-7	2011	The GABA(B) agonist baclofen inhibited the amplitude of ST-EPSCs from both TRPV1+ and TRPV1- afferents with a similar EC(50) (~1.2 muM).	gamma-Aminobutyric Acid	4-8	transient receptor potential cation channel subfamily V member 1	Homo sapiens	86-91	
21734101-9	2011	With calcium entry through voltage-activated calcium channels blocked by cadmium, baclofen reduced mEPSC frequency, indicating that GABA(B) reduced vesicle release by TRPV1-dependent calcium entry.	gamma-Aminobutyric Acid	132-136	transient receptor potential cation channel subfamily V member 1	Homo sapiens	167-172	
21734101-10	2011	GABA(B) activation also reduced temperature-evoked increases in mEPSC frequency, which relies on TRPV1.	gamma-Aminobutyric Acid	0-4	transient receptor potential cation channel subfamily V member 1	Homo sapiens	97-102	
21734101-11	2011	Our studies indicate that GABA(B) G protein-coupled receptors are uniformly distributed across all ST primary afferent terminals and act at multiple stages of the excitation-release cascades to suppress both action potential-triggered and TRPV1-coupled glutamate transmission pathways.	gamma-Aminobutyric Acid	26-30	transient receptor potential cation channel subfamily V member 1	Homo sapiens	239-244	
21645527-10	2011	We demonstrate that the enhancement mediated by TRPV1 agonists requires GABA input to pyramidal cells thus providing a mechanism for how TRPV1 agonists modulate hippocampal synaptic plasticity.	gamma-Aminobutyric Acid	72-76	transient receptor potential cation channel subfamily V member 1	Homo sapiens	48-53	
21645527-10	2011	We demonstrate that the enhancement mediated by TRPV1 agonists requires GABA input to pyramidal cells thus providing a mechanism for how TRPV1 agonists modulate hippocampal synaptic plasticity.	gamma-Aminobutyric Acid	72-76	transient receptor potential cation channel subfamily V member 1	Homo sapiens	137-142