PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18160701-6 2007 Conversely, attenuated GABA release in response to activation of inhibitory 5-HT heteroreceptors, e.g., 5-HT(1A) or 5-HT(1B) receptors on GABAergic interneurons is involved in paradoxical facilitation of hippocampal acetylcholine and striatal dopamine release, respectively. gamma-Aminobutyric Acid 23-27 5-hydroxytryptamine receptor 1B Homo sapiens 116-123 28735749-3 2017 In these neurons, 5-HT1B receptors are expressed presynaptically, and their activation inhibits GABA release. gamma-Aminobutyric Acid 96-100 5-hydroxytryptamine receptor 1B Homo sapiens 18-24 17511969-10 2007 Moreover, MDMA depressed the GABA(B) IPSP by activating 5-HT 1B receptors. gamma-Aminobutyric Acid 29-33 5-hydroxytryptamine receptor 1B Homo sapiens 56-63 12486179-4 2002 One possibility is that 5-HT1B receptors on the terminals of GABAergic projections from NAcc to VTA inhibit local GABA release, thereby disinhibiting VTA neurons. gamma-Aminobutyric Acid 61-65 5-hydroxytryptamine receptor 1B Homo sapiens 24-30 15527863-8 2004 The regulation of gamma-aminobutyric acid release by 5-HT1B receptors has been found in projections: from caudate putamen to the globus pallidus or substantia nigra, from nucleus accumbens to the ventral tegmentum area, and from purkinje neurons to the deep nuclei of the cerebellum. gamma-Aminobutyric Acid 18-41 5-hydroxytryptamine receptor 1B Homo sapiens 53-59 12397864-3 2001 5-HT1B receptors inhibit the release of a range of neurotransmitters, including serotonin, GABA, acetylcholine, and glutamate. gamma-Aminobutyric Acid 91-95 5-hydroxytryptamine receptor 1B Homo sapiens 0-6 9378233-6 1997 Presynaptic 5-HT 1B/D receptors take part in the control of the release not only of 5-HT itself, but also of other neurotransmitters-for example, acetylcholine, glutamate, dopamine, noradrenaline and gamma-aminobutyric acid. gamma-Aminobutyric Acid 200-223 5-hydroxytryptamine receptor 1B Homo sapiens 12-19 23486958-8 2013 5-HT and CP93129 also decreased the amplitude but increased the paired pulse ratio of the monosynaptic EPSCs in SNr GABA neurons, indicating a presynaptic 5-HT1B receptor-mediated inhibition of glutamate release. gamma-Aminobutyric Acid 116-120 5-hydroxytryptamine receptor 1B Homo sapiens 155-161 25787955-3 2015 In this article we show that 5-HT, by activating presynaptic 5-HT(1B)Rs on the striatonigral axon terminals, potently inhibited the striatonigral GABA output, as reflected in the reduction of the striatonigral inhibitory postsynaptic currents in SNr GABA neurons. gamma-Aminobutyric Acid 146-150 5-hydroxytryptamine receptor 1B Homo sapiens 61-68 25787955-3 2015 In this article we show that 5-HT, by activating presynaptic 5-HT(1B)Rs on the striatonigral axon terminals, potently inhibited the striatonigral GABA output, as reflected in the reduction of the striatonigral inhibitory postsynaptic currents in SNr GABA neurons. gamma-Aminobutyric Acid 250-254 5-hydroxytryptamine receptor 1B Homo sapiens 61-68 25787955-4 2015 Functionally, 5-HT(1B)R agonism reduced the striatonigral GABA output-induced pause of the spontaneous high-frequency firing in SNr GABA neurons. gamma-Aminobutyric Acid 58-62 5-hydroxytryptamine receptor 1B Homo sapiens 14-21 25787955-4 2015 Functionally, 5-HT(1B)R agonism reduced the striatonigral GABA output-induced pause of the spontaneous high-frequency firing in SNr GABA neurons. gamma-Aminobutyric Acid 132-136 5-hydroxytryptamine receptor 1B Homo sapiens 14-21 25787955-5 2015 Equally important, chronic SSRI treatment with fluoxetine enhanced this presynaptic 5-HT(1B)R-mediated pause reduction in SNr GABA neurons. gamma-Aminobutyric Acid 126-130 5-hydroxytryptamine receptor 1B Homo sapiens 84-91 25787955-6 2015 Taken together, these results indicate that activation of the 5-HT(1B)Rs on the striatonigral axon terminals can limit the motor-promoting GABA output. gamma-Aminobutyric Acid 139-143 5-hydroxytryptamine receptor 1B Homo sapiens 62-69 28553205-4 2017 On the other hand, presynaptic inhibition of the GABA release onto cholinergic neurons mediated by D1-like receptors or 5-HT1B receptors is independent of calcium influx. gamma-Aminobutyric Acid 49-53 5-hydroxytryptamine receptor 1B Homo sapiens 120-126 23486958-10 2013 Finally, the 5-HT1B receptor antagonist NAS-181 increased the STN-triggered complex EPSCs and burst firing in SNr GABA neurons, demonstrating the effects of endogenous 5-HT. gamma-Aminobutyric Acid 114-118 5-hydroxytryptamine receptor 1B Homo sapiens 13-19 23486958-11 2013 These results suggest that nigral 5-HT, via presynaptic 5-HT1B receptor activation, gates the excitatory STN SNr projection, reduces burst firing in SNr GABA neurons, and thus may play a critical role in movement control. gamma-Aminobutyric Acid 153-157 5-hydroxytryptamine receptor 1B Homo sapiens 56-62 18632894-3 2008 Previous findings suggest that the presynaptic 5-HT1B receptor may act to decrease the release of GABA onto IC neurons. gamma-Aminobutyric Acid 98-102 5-hydroxytryptamine receptor 1B Homo sapiens 47-53 23118018-5 2013 Furthermore, 5-HT1B auto- and hetero-receptors regulate alcohol intake through the regulatory mechanism involving release of 5-HT, gamma-aminobutyric acid (GABA), dopamine, and glutamate is evaluated. gamma-Aminobutyric Acid 131-154 5-hydroxytryptamine receptor 1B Homo sapiens 13-19 23118018-5 2013 Furthermore, 5-HT1B auto- and hetero-receptors regulate alcohol intake through the regulatory mechanism involving release of 5-HT, gamma-aminobutyric acid (GABA), dopamine, and glutamate is evaluated. gamma-Aminobutyric Acid 156-160 5-hydroxytryptamine receptor 1B Homo sapiens 13-19 20480149-8 2011 Abnormal 5-HT(1B) heteroreceptor function may contribute to dysfunctional reward signaling within the striatum, including the nucleus accumbens, via interaction with dopamine, gamma-amino-butyric acid, or glutamate systems. gamma-Aminobutyric Acid 176-200 5-hydroxytryptamine receptor 1B Homo sapiens 9-16