PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23103406-15	2013	The current study shows that 5-HT(2C) receptor activity exerts an inhibitory influence on the short-term and long-term behavioral responses to cocaine.	Cocaine	143-150	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	29-46	
30578419-0	2019	Serotonin transporter inhibition and 5-HT2C receptor activation drive loss of cocaine-induced locomotor activation in DAT Val559 mice.	Cocaine	78-85	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	37-43	
25656481-1	2015	The serotonin system is intimately linked to both the mediation of anxiety and long-term effects of cocaine, potentially through interaction of inhibitory 5-HT2C receptor and gamma-aminobutyric acid (GABA) networks.	Cocaine	100-107	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	155-170	
25656481-2	2015	This study characterized the function of the dorsal raphe (DR) 5-HT2C receptor and GABA network in anxiety produced by chronic cocaine withdrawal.	Cocaine	127-134	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	63-78	
25656481-8	2015	In a separate cohort of cocaine-injected mice at 25 h of withdrawal, both global and intra-DR blockade of 5-HT2C receptors prior to elevated plus maze testing attenuated anxiety-like behavior.	Cocaine	24-31	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	106-112	
25656481-9	2015	This study demonstrates that DR 5-HT2C receptor blockade prevents anxiety-like behavior produced by cocaine withdrawal, potentially through attenuation of heightened GABA activity, supporting a role for the 5-HT2C receptor in mediating anxiety produced by cocaine withdrawal.	Cocaine	100-107	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	32-47	
24979384-6	2014	LV-MBII-52 and LV-5HT2CR expression in NAc attenuate cocaine induced CPP and locomotor activity.	Cocaine	53-60	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	18-24	
24979384-7	2014	Taken together, these findings show that MBII-52 and 5HT2CR exert an inhibitory influence on the behavioral responses to cocaine exposure.	Cocaine	121-128	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	53-59	
20624416-1	2010	Previous work showed that 5-HT(2C) receptor agonists reduce cocaine self-administration on a progressive ratio (PR) schedule of reinforcement, whereas a 5-HT(2C) receptor antagonist enhances responding for cocaine.	Cocaine	60-67	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	26-43	
20624416-1	2010	Previous work showed that 5-HT(2C) receptor agonists reduce cocaine self-administration on a progressive ratio (PR) schedule of reinforcement, whereas a 5-HT(2C) receptor antagonist enhances responding for cocaine.	Cocaine	206-213	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	153-170	
16125150-11	2005	These results suggest that the increase of serotonergic neuronal activity through 5-HT2C receptor stimulation was responsible for increased activity of local anesthetics-induced convulsions and support the involvement of this mechanism in cocaine- and meprylcaine- but not in lidocaine-induced convulsions through their direct inhibitory action on central SERT.	Cocaine	239-246	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	82-97	
12427861-7	2002	These findings strongly implicate 5-HT2C receptors in the serotonergic suppression of DA-mediated behavioral responses to cocaine and as a potential therapeutic target for cocaine abuse.	Cocaine	122-129	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	34-40