PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25586717-3 2015 Additionally, we have previously reported a decrease in retinoid-X-receptor-gamma (RXR-gamma) in brains of mice chronically exposed to cocaine. Cocaine 135-142 retinoid X receptor gamma Mus musculus 56-81 25586717-3 2015 Additionally, we have previously reported a decrease in retinoid-X-receptor-gamma (RXR-gamma) in brains of mice chronically exposed to cocaine. Cocaine 135-142 retinoid X receptor gamma Mus musculus 83-92 25586717-6 2015 To evaluate the mechanism underlying the cocaine-induced decreases in RXR-gamma levels observed in vivo, we exposed neurons to cocaine in vitro and examined pathways which may contribute to disruption in RXR signaling, including activation of stress pathways by cytokine induction. Cocaine 41-48 retinoid X receptor gamma Mus musculus 70-79 25586717-7 2015 In these studies, we provide the first evidence that cocaine exposure disrupts neuronal RXR-gamma signaling in vitro by promoting its nuclear export and degradation. Cocaine 53-60 retinoid X receptor gamma Mus musculus 88-97