PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35508123-2 2022 In this study, we show that cocaine exposure worsens the learning and memory of doxycycline-inducible and brain-specific HIV Tat transgenic mice (iTat) and results in 14,838 hypermethylated CpG-related differentially methylated regions (DMRs) and 15,800 hypomethylated CpG-related DMRs, which are linked to 52 down- and 127 upregulated genes, respectively, in the hippocampus of iTat mice. Cocaine 28-35 tyrosine aminotransferase Mus musculus 125-128 30948476-4 2019 Cocaine-conditioned place preference behavior and ex vivo whole-cell electrophysiology showed that cocaine-primed reinstatement and synaptic depotentiation were disrupted by inhibiting AMPAR internalization via intra-NAc shell infusion of a Tat-GluA23Y peptide. Cocaine 99-106 tyrosine aminotransferase Mus musculus 241-244 23945478-5 2014 Compared with uninduced littermates or C57BL/6J controls, cocaine-induced hyperlocomotion was sustained for a significantly longer duration among Tat-induced mice. Cocaine 58-65 tyrosine aminotransferase Mus musculus 146-149 23945478-9 2014 Re-exposure to cocaine produced reinstatement of an equivalent place preference in Tat-induced GT-tg or C57BL/6J mice; however, induction of Tat protein after the extinction of CPP also produced reinstatement without additional exposure to cocaine. Cocaine 15-22 tyrosine aminotransferase Mus musculus 83-86