PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12657709-1	2003	The transcription factor DeltaFosB accumulates in substance P-dynorphin-containing striatal neurons with repeated cocaine use.	Cocaine	114-121	tachykinin 1	Mus musculus	50-61	
16899413-6	2006	NK1 antagonists alone did not have any rewarding or aversive effect in the CPP suggesting that substance P opposes some of the unpleasant effects of morphine and cocaine.	Cocaine	162-169	tachykinin 1	Mus musculus	95-106	
9691193-5	1998	Acute cocaine administration increases substance P levels, suggesting that striatal expression of this neuropeptide can be modulated by D1R-independent processes.	Cocaine	6-13	tachykinin 1	Mus musculus	39-50	
8884777-0	1996	D1 dopamine receptor-deficient mouse: cocaine-induced regulation of immediate-early gene and substance P expression in the striatum.	Cocaine	38-45	tachykinin 1	Mus musculus	93-104	
8884777-7	1996	These results demonstrate that some of the effects of cocaine on gene regulation are mediated via D1 receptor-dependent mechanisms, as evidenced by the absence of immediate-early gene induction in D1-deficient mice, whereas others also involve additional, non-D1 receptor mechanisms, as shown for substance P expression.	Cocaine	54-61	tachykinin 1	Mus musculus	297-308