PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11597771-13 2001 The results suggest that the cocaine-induced modulation of hypothalamic CRH mRNA expression is secondary to changes in the activity of specific components of dopaminergic systems. Cocaine 29-36 corticotropin releasing hormone Rattus norvegicus 72-75 11734187-2 2001 Although the role of corticotropin releasing hormone (CRH) in stress- and cocaine-induced relapse has been reported, its involvement in cue-induced behavior has not been established. Cocaine 74-81 corticotropin releasing hormone Rattus norvegicus 21-52 11734187-2 2001 Although the role of corticotropin releasing hormone (CRH) in stress- and cocaine-induced relapse has been reported, its involvement in cue-induced behavior has not been established. Cocaine 74-81 corticotropin releasing hormone Rattus norvegicus 54-57 9651233-0 1998 The role of corticotropin-releasing factor and corticosterone in stress- and cocaine-induced relapse to cocaine seeking in rats. Cocaine 77-84 corticotropin releasing hormone Rattus norvegicus 12-42 11027923-1 2000 The role for corticotropin-releasing hormone (CRH) receptors in the maintenance of intravenous cocaine self-administration in rats was investigated using the centrally active, small molecule CRH1 receptor antagonist CP-154,526. Cocaine 95-102 corticotropin releasing hormone Rattus norvegicus 13-44 11027923-1 2000 The role for corticotropin-releasing hormone (CRH) receptors in the maintenance of intravenous cocaine self-administration in rats was investigated using the centrally active, small molecule CRH1 receptor antagonist CP-154,526. Cocaine 95-102 corticotropin releasing hormone Rattus norvegicus 46-49 11027923-7 2000 Furthermore, responding on the cocaine lever following CP-154,526 pretreatment was significantly suppressed, even during the first 15 min of the session, a time when rats typically sample the cocaine lever during extinction, suggesting that CRH receptors may also be involved in some of the conditioned effects of cocaine as well. Cocaine 31-38 corticotropin releasing hormone Rattus norvegicus 241-244 11027923-8 2000 These data are discussed in terms of the role for CRH in the neurobehavioral effects of cocaine. Cocaine 88-95 corticotropin releasing hormone Rattus norvegicus 50-53 11222986-0 2001 Central corticotropin releasing factor (CRF) and adrenergic receptors mediate hemodynamic responses to cocaine. Cocaine 103-110 corticotropin releasing hormone Rattus norvegicus 8-38 10516337-0 1999 A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotropin-releasing factor on stress-induced reinstatement of cocaine seeking. Cocaine 158-165 corticotropin releasing hormone Rattus norvegicus 92-122 10445369-0 1999 Corticotropin-releasing factor antagonist attenuates the "anxiogenic-like" effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats. Cocaine 168-175 corticotropin releasing hormone Rattus norvegicus 0-30 9651233-0 1998 The role of corticotropin-releasing factor and corticosterone in stress- and cocaine-induced relapse to cocaine seeking in rats. Cocaine 104-111 corticotropin releasing hormone Rattus norvegicus 12-42 9068125-0 1997 Regional binding to corticotropin releasing factor receptors in brain of rats exposed to chronic cocaine and cocaine withdrawal. Cocaine 97-104 corticotropin releasing hormone Rattus norvegicus 20-50 9630005-1 1998 We have found that peptide antagonists of corticotropin-releasing factor (CRF) receptors attenuate reinstatement of heroin and cocaine seeking induced by footshock. Cocaine 127-134 corticotropin releasing hormone Rattus norvegicus 42-72 9566810-0 1998 Corticotropin-releasing factor receptor blockade enhances conditioned aversive properties of cocaine in rats. Cocaine 93-100 corticotropin releasing hormone Rattus norvegicus 0-30 9554945-0 1998 Conditioned release of corticosterone by contextual stimuli associated with cocaine is mediated by corticotropin-releasing factor. Cocaine 76-83 corticotropin releasing hormone Rattus norvegicus 99-129 9197270-1 1997 Corticotropin-releasing factor (CRF) has been implicated in the mediation of the stress-like and negative affective consequences of withdrawal from drugs of abuse, such as alcohol, cocaine, and opiates. Cocaine 181-188 corticotropin releasing hormone Rattus norvegicus 0-30 9068125-1 1997 Cocaine, as does exposure to other physiological stressors, releases brain corticotropin releasing factor (CRF), and this release habituates during the course of repeated cocaine administration in animals. Cocaine 0-7 corticotropin releasing hormone Rattus norvegicus 75-105 9068125-1 1997 Cocaine, as does exposure to other physiological stressors, releases brain corticotropin releasing factor (CRF), and this release habituates during the course of repeated cocaine administration in animals. Cocaine 171-178 corticotropin releasing hormone Rattus norvegicus 75-105 9574831-0 1997 Time-dependent alterations in corticotropin-releasing factor-like immunoreactivity in different brain regions after acute cocaine administration to rats. Cocaine 122-129 corticotropin releasing hormone Rattus norvegicus 30-60 9574831-1 1997 Recent data from various laboratories suggest that the activation of endogenous corticotropin-releasing factor (CRF) may contribute to the behavioral and neuroendocrine effects of cocaine. Cocaine 180-187 corticotropin releasing hormone Rattus norvegicus 80-110 8100073-1 1993 It has previously been demonstrated that cocaine stimulates the hypothalamic-pituitary-adrenal (HPA) axis through hypothalamic corticotropin-releasing factor (CRF) secretion. Cocaine 41-48 corticotropin releasing hormone Rattus norvegicus 127-157 8859013-0 1996 Corticotropin-releasing factor and type 1 corticotropin-releasing factor receptor messenger RNAs in rat brain and pituitary during "binge"-pattern cocaine administration and chronic withdrawal. Cocaine 147-154 corticotropin releasing hormone Rattus norvegicus 0-30 8859013-0 1996 Corticotropin-releasing factor and type 1 corticotropin-releasing factor receptor messenger RNAs in rat brain and pituitary during "binge"-pattern cocaine administration and chronic withdrawal. Cocaine 147-154 corticotropin releasing hormone Rattus norvegicus 42-72 8859013-1 1996 Endogenous central corticotropin-releasing factor (CRF) may be involved in the neuroendocrine and behavioral responses to cocaine. Cocaine 122-129 corticotropin releasing hormone Rattus norvegicus 19-49 7796157-0 1995 Brain corticotropin-releasing factor mediates "anxiety-like" behavior induced by cocaine withdrawal in rats. Cocaine 81-88 corticotropin releasing hormone Rattus norvegicus 6-36 7796157-2 1995 Corticotropin-releasing factor (CRF) plays an important role in the pathophysiology of anxiety and depression, and it may also be involved in the acute behavioral and neuroendocrine actions of cocaine. Cocaine 193-200 corticotropin releasing hormone Rattus norvegicus 0-30 7624019-0 1995 Sensitization of cocaine-stimulated increase in extracellular levels of corticotropin-releasing factor from the rat amygdala after repeated administration as determined by intracranial microdialysis. Cocaine 17-24 corticotropin releasing hormone Rattus norvegicus 72-102 7673418-1 1995 Cocaine stimulates ACTH secretion by a corticotropin-releasing factor (CRF)-dependent mechanism in male rats, rhesus monkeys, and humans. Cocaine 0-7 corticotropin releasing hormone Rattus norvegicus 39-69 8358623-0 1993 Alterations of corticotropin-releasing factor-like immunoreactivity in different brain regions after acute cocaine administration in rats. Cocaine 107-114 corticotropin releasing hormone Rattus norvegicus 15-45 8358623-1 1993 Corticotropin-releasing factor (CRF) may mediate some of the neuroendocrine and behavioral responses to cocaine. Cocaine 104-111 corticotropin releasing hormone Rattus norvegicus 0-30 1330207-0 1992 The cocaine-induced elevation of plasma corticosterone is mediated by endogenous corticotropin-releasing factor (CRF) in rats. Cocaine 4-11 corticotropin releasing hormone Rattus norvegicus 81-111 1330207-1 1992 The role of endogenous corticotropin-releasing factor (CRF) in the cocaine-induced corticosterone response was investigated by using the immunoneutralization and receptor blockade of endogenous CRF. Cocaine 67-74 corticotropin releasing hormone Rattus norvegicus 23-53 1324099-2 1992 Intravenous injections of synthetic corticotropin-releasing factor (CRF) (0.2, 1, or 5 micrograms/kg) elicited dose-dependent increases in ACTH secretion irrespective of whether rats had been previously exposed to cocaine or not. Cocaine 214-221 corticotropin releasing hormone Rattus norvegicus 36-66 35503756-0 2022 Corticotropin releasing factor (CRF) systems: Promoting cocaine pursuit without distress via incentive motivation. Cocaine 56-63 corticotropin releasing hormone Rattus norvegicus 0-30 1335535-0 1992 Critical role of endogenous corticotropin-releasing factor (CRF) in the mediation of the behavioral action of cocaine in rats. Cocaine 110-117 corticotropin releasing hormone Rattus norvegicus 28-58 2611679-0 1989 Cocaine stimulates rat hypothalamic corticotropin-releasing hormone secretion in vitro. Cocaine 0-7 corticotropin releasing hormone Rattus norvegicus 36-67 2611679-9 1989 On the other hand, cocaine-induced iCRH secretion was inhibited by GABA, a potent inhibitor of CRH secretion, dexamethasone, verapamil, a calcium channel blocker, tetrodotoxin, a sodium channel blocker, and carbamazepine, an antiepileptic and antidepressive agent. Cocaine 19-26 corticotropin releasing hormone Rattus norvegicus 36-39 30885137-1 2019 BACKGROUND: Pre-treatment with the corticotropin-releasing factor antagonist alpha-helical CRF9-41 prevents inhibition of gastric emptying by cocaine-and amphetamine-regulated transcript peptide at a dorsal hindbrain level, but its inhibition of sucrose intake is not affected. Cocaine 142-149 corticotropin releasing hormone Rattus norvegicus 35-65 2823980-0 1987 Cocaine stimulates adrenocorticotropin (ACTH) secretion through a corticotropin-releasing factor (CRF)-mediated mechanism. Cocaine 0-7 corticotropin releasing hormone Rattus norvegicus 66-96 2823980-2 1987 The observation that this stimulatory effect was completely abolished by pretreatment with a corticotropin-releasing factor (CRF) antiserum, coupled with the lack of effect of cocaine on ACTH secretion by cultured pituitary cells, suggests that cocaine acts within the brain to release endogenous CRF. Cocaine 245-252 corticotropin releasing hormone Rattus norvegicus 93-123 31984611-7 2021 In addition, corticotropin-releasing factor (CRF) was increased in the bed nucleus of stria terminalis after cocaine CPP. Cocaine 109-116 corticotropin releasing hormone Rattus norvegicus 13-43 30885137-7 2019 CONCLUSIONS: We conclude that an endogenous Corticotropin-releasing factor agonist may modulate suppression of food intake caused by cocaine-and amphetamine-regulated transcript peptide at a dorsal hindbrain level in the absence of stress. Cocaine 133-140 corticotropin releasing hormone Rattus norvegicus 44-74 30885137-8 2019 A potential caudal brainstem mechanism whereby cocaine-and amphetamine-regulated transcript peptide effects on food intake is attenuated via corticotropin-releasing factor receptor activity causing tonic inhibition, is suggested. Cocaine 47-54 corticotropin releasing hormone Rattus norvegicus 141-171 27181613-12 2016 Rats that self-administered cocaine displayed greater CRH expression in the amygdala that was independent of urine exposure. Cocaine 28-35 corticotropin releasing hormone Rattus norvegicus 54-57 30355627-2 2018 This study examined the role of a corticotropin releasing factor (CRF)-regulated dopaminergic projection from the ventral tegmental area (VTA) to the prelimbic cortex in shock-induced cocaine seeking and its recruitment under self-administration conditions that establish relapse vulnerability. Cocaine 184-191 corticotropin releasing hormone Rattus norvegicus 34-64 30355627-10 2018 Prior work has demonstrated a critical role for the neuropeptide corticotropin releasing factor (CRF) in stress-induced cocaine seeking. Cocaine 120-127 corticotropin releasing hormone Rattus norvegicus 65-95 27362504-0 2016 Role of Corticotropin Releasing Factor 1 Signaling in Cocaine Seeking during Early Extinction in Female and Male Rats. Cocaine 54-61 corticotropin releasing hormone Rattus norvegicus 8-38 24768621-0 2014 Repeated intravenous administrations of teneurin-C terminal associated peptide (TCAP)-1 attenuates reinstatement of cocaine seeking by corticotropin-releasing factor (CRF) in rats. Cocaine 116-123 corticotropin releasing hormone Rattus norvegicus 135-165 26318765-2 2015 Here, we explored the effect of repeated immobilization stress on cocaine-induced increase in dopamine extracellular levels in VTA and its regulation by corticotropin-releasing factor (CRF) and GABA systems. Cocaine 66-73 corticotropin releasing hormone Rattus norvegicus 153-183 25926444-0 2015 Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine. Cocaine 103-110 corticotropin releasing hormone Rattus norvegicus 7-37 25209288-2 2014 Here we demonstrate that, in the vBNST, corticotropin releasing factor (CRF) is expressed in neurons that innervate the ventral tegmental area (VTA), a site where the CRF receptor antagonist antalarmin prevents the reinstatement of cocaine seeking by a stressor, intermittent footshock, following intravenous self-administration in rats. Cocaine 232-239 corticotropin releasing hormone Rattus norvegicus 33-70 25073922-2 2014 Repeated treatment with cocaine potentiates glutamatergic transmission in the rat basolateral amygdala/cortex pathway through a synergistic action of D1 -like dopamine receptors and CRH type-2alpha receptors (CRF2 alpha receptors). Cocaine 24-31 corticotropin releasing hormone Rattus norvegicus 182-185 22707255-0 2012 Reinstatement of cocaine seeking in rats by the pharmacological stressors, corticotropin-releasing factor and yohimbine: role for D1/5 dopamine receptors. Cocaine 17-24 corticotropin releasing hormone Rattus norvegicus 75-105 21813699-2 2011 Excessive cocaine use may increase susceptibility to stressor-induced relapse through alterations in brain corticotropin-releasing factor (CRF) regulation of neurocircuitry involved in drug seeking. Cocaine 10-17 corticotropin releasing hormone Rattus norvegicus 107-137 22489809-0 2012 Cannabinoid CB1 receptors mediate the effects of corticotropin-releasing factor on the reinstatement of cocaine seeking and expression of cocaine-induced behavioural sensitization. Cocaine 104-111 corticotropin releasing hormone Rattus norvegicus 49-79 22489809-0 2012 Cannabinoid CB1 receptors mediate the effects of corticotropin-releasing factor on the reinstatement of cocaine seeking and expression of cocaine-induced behavioural sensitization. Cocaine 138-145 corticotropin releasing hormone Rattus norvegicus 49-79 22489809-1 2012 BACKGROUND AND PURPOSE: The endocannabinoid and corticotropin-releasing factor (CRF) systems have been implicated in several long-lasting behavioural effects of prior cocaine experience. Cocaine 167-174 corticotropin releasing hormone Rattus norvegicus 48-78 21762287-0 2012 Extended access cocaine self-administration differentially activates dorsal raphe and amygdala corticotropin-releasing factor systems in rats. Cocaine 16-23 corticotropin releasing hormone Rattus norvegicus 95-125 21762287-2 2012 The present study tested the hypothesis that rats receiving extended versus brief daily access to cocaine would exhibit regional differences in levels of the stress-regulatory neuropeptide corticotropin-releasing factor (CRF). Cocaine 98-105 corticotropin releasing hormone Rattus norvegicus 189-219 19251246-2 2009 Intra-VTA Hcrt reinstates morphine-conditioned place preferences, and intracerebroventricular and intra-VTA corticotropin-releasing factor (CRF) reinstate cocaine seeking. Cocaine 155-162 corticotropin releasing hormone Rattus norvegicus 108-138 20883474-0 2011 Teneurin C-terminal associated peptide-1 blocks the effects of corticotropin-releasing factor on reinstatement of cocaine seeking and on cocaine-induced behavioural sensitization. Cocaine 114-121 corticotropin releasing hormone Rattus norvegicus 63-93 20883474-1 2011 BACKGROUND AND PURPOSE: The stress-related neuropeptide, corticotropin-releasing factor (CRF), has become an important focus of studies of cocaine addiction, and in particular, the effects of stress on cocaine-related behaviours. Cocaine 139-146 corticotropin releasing hormone Rattus norvegicus 57-87 21075083-0 2011 Effects of perinatal cocaine exposure on open field behavior and the response to corticotropin releasing hormone (CRH) in rat offspring. Cocaine 21-28 corticotropin releasing hormone Rattus norvegicus 81-112 21075083-0 2011 Effects of perinatal cocaine exposure on open field behavior and the response to corticotropin releasing hormone (CRH) in rat offspring. Cocaine 21-28 corticotropin releasing hormone Rattus norvegicus 114-117 20377617-0 2010 Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal. Cocaine 129-136 corticotropin releasing hormone Rattus norvegicus 37-67 17437087-1 2007 RATIONALE: Footshock reinstates cocaine seeking in cocaine-experienced rats by inducing corticotropin-releasing factor (CRF) and glutamate release in the ventral tegmental area (VTA) and thus activating VTA dopaminergic neurons. Cocaine 32-39 corticotropin releasing hormone Rattus norvegicus 88-118 18596687-2 2009 Here, we report the efficacy of betaxolol in reducing increases in gene expression of amygdalar corticotropin-releasing factor (CRF), a peptide known to be involved in mediating "anxiety-like" behaviors during initial phases of cocaine abstinence. Cocaine 228-235 corticotropin releasing hormone Rattus norvegicus 96-126 17899015-2 2008 Excessive cocaine use may increase susceptibility to stressor-induced relapse through alterations in brain corticotropin-releasing factor (CRF) responsiveness. Cocaine 10-17 corticotropin releasing hormone Rattus norvegicus 107-137 17437087-1 2007 RATIONALE: Footshock reinstates cocaine seeking in cocaine-experienced rats by inducing corticotropin-releasing factor (CRF) and glutamate release in the ventral tegmental area (VTA) and thus activating VTA dopaminergic neurons. Cocaine 51-58 corticotropin releasing hormone Rattus norvegicus 88-118 15986362-0 2005 Effects of corticotropin-releasing hormone receptor antagonists on cocaine-induced dopamine overflow in the medial prefrontal cortex and nucleus accumbens of rats. Cocaine 67-74 corticotropin releasing hormone Rattus norvegicus 11-42 17293045-0 2007 Restraint-induced corticosterone secretion and hypothalamic CRH mRNA expression are augmented during acute withdrawal from chronic cocaine administration. Cocaine 131-138 corticotropin releasing hormone Rattus norvegicus 60-63 15986362-2 2005 CRH receptor antagonists reduce cocaine self-administration and attenuate the reinstatement of extinguished cocaine-seeking behavior, but little is known about the mechanisms involved. Cocaine 32-39 corticotropin releasing hormone Rattus norvegicus 0-3 15986362-3 2005 One possible mechanism for these effects may involve the cocaine-induced activation of CRH located in brain regions outside of the hypothalamus. Cocaine 57-64 corticotropin releasing hormone Rattus norvegicus 87-90 15986362-4 2005 CRH has been shown to increase dopaminergic transmission in regions relevant for cocaine reinforcement, such as the medial prefrontal cortex and the nucleus accumbens. Cocaine 81-88 corticotropin releasing hormone Rattus norvegicus 0-3 15986362-7 2005 These data suggest a surprising role for prefrontal cortex dopamine in the ability of CRH-receptor antagonists to attenuate cocaine seeking in rats. Cocaine 124-131 corticotropin releasing hormone Rattus norvegicus 86-89 15680464-0 2005 Role of angiotensin II and corticotropin-releasing hormone in hemodynamic responses to cocaine and stress. Cocaine 87-94 corticotropin releasing hormone Rattus norvegicus 27-58 15955413-1 2005 There is evidence that cocaine pre-exposure produces changes in the responsivity of central corticotropin-releasing factor (CRF) systems and that these systems mediate some of the drug-related behavioural effects of acute stressors. Cocaine 23-30 corticotropin releasing hormone Rattus norvegicus 92-122 15930388-0 2005 Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking. Cocaine 0-7 corticotropin releasing hormone Rattus norvegicus 77-107 15930388-1 2005 Footshock stress can reinstate cocaine-seeking behavior through a central action of the stress-associated neurohormone corticotropin-releasing factor (CRF). Cocaine 31-38 corticotropin releasing hormone Rattus norvegicus 119-149 12955298-0 2003 Prior, repeated exposure to cocaine potentiates locomotor responsivity to central injections of corticotropin-releasing factor (CRF) in rats. Cocaine 28-35 corticotropin releasing hormone Rattus norvegicus 96-126 12955298-1 2003 RATIONALE: There is considerable evidence that the stress-related neuropeptide, corticotropin-releasing factor (CRF), plays an important role in mediating behavioural changes induced by prior experience with cocaine. Cocaine 208-215 corticotropin releasing hormone Rattus norvegicus 80-110 14559150-0 2003 Extinction of cocaine self-administration produces alterations in corticotropin releasing factor gene expression in the paraventricular nucleus of the hypothalamus. Cocaine 14-21 corticotropin releasing hormone Rattus norvegicus 66-96 14559150-1 2003 The long-term effect of cocaine self-administration on corticotropin releasing factor (CRF) mRNA content in the hypothalamic CRF-containing neurons has not yet been established. Cocaine 24-31 corticotropin releasing hormone Rattus norvegicus 55-85 12614338-0 2003 Dopamine-dependent responses to cocaine depend on corticotropin-releasing factor receptor subtypes. Cocaine 32-39 corticotropin releasing hormone Rattus norvegicus 50-80 12576179-2 2003 This blunting of HPA axis activity in response to cocaine is associated with a cocaine-induced reduction of corticotropin-releasing hormone (CRH) mRNA level in the hypothalamus. Cocaine 50-57 corticotropin releasing hormone Rattus norvegicus 108-139 12576179-2 2003 This blunting of HPA axis activity in response to cocaine is associated with a cocaine-induced reduction of corticotropin-releasing hormone (CRH) mRNA level in the hypothalamus. Cocaine 50-57 corticotropin releasing hormone Rattus norvegicus 141-144 12576179-2 2003 This blunting of HPA axis activity in response to cocaine is associated with a cocaine-induced reduction of corticotropin-releasing hormone (CRH) mRNA level in the hypothalamus. Cocaine 79-86 corticotropin releasing hormone Rattus norvegicus 108-139 12576179-2 2003 This blunting of HPA axis activity in response to cocaine is associated with a cocaine-induced reduction of corticotropin-releasing hormone (CRH) mRNA level in the hypothalamus. Cocaine 79-86 corticotropin releasing hormone Rattus norvegicus 141-144 15519677-0 2004 Effects of selective D1- or D2-like dopamine receptor antagonists with acute "binge" pattern cocaine on corticotropin-releasing hormone and proopiomelanocortin mRNA levels in the hypothalamus. Cocaine 93-100 corticotropin releasing hormone Rattus norvegicus 104-135 15519677-1 2004 We have previously demonstrated that there are stimulatory effects of acute (1 day) "binge" cocaine on corticotropin-releasing hormone (CRH) gene expression in the rat hypothalamus and on the stress responsive hypothalamic-pituitary-adrenal (HPA) activity. Cocaine 92-99 corticotropin releasing hormone Rattus norvegicus 103-134 15519677-1 2004 We have previously demonstrated that there are stimulatory effects of acute (1 day) "binge" cocaine on corticotropin-releasing hormone (CRH) gene expression in the rat hypothalamus and on the stress responsive hypothalamic-pituitary-adrenal (HPA) activity. Cocaine 92-99 corticotropin releasing hormone Rattus norvegicus 136-139 15288701-7 2004 Since the MPC and CRH have been implicated in the neurobiology of cocaine, CRH-induced alterations in dopaminergic neurotransmission may play an important role in this peptide"s effects on cocaine responsiveness. Cocaine 66-73 corticotropin releasing hormone Rattus norvegicus 18-21 15288701-7 2004 Since the MPC and CRH have been implicated in the neurobiology of cocaine, CRH-induced alterations in dopaminergic neurotransmission may play an important role in this peptide"s effects on cocaine responsiveness. Cocaine 66-73 corticotropin releasing hormone Rattus norvegicus 75-78 15288701-8 2004 Taken together with the results from previous studies, these data suggest that ketoconazole may affect cocaine reward, at least in part, through interactions with dopamine and CRH within the MPC. Cocaine 103-110 corticotropin releasing hormone Rattus norvegicus 176-179 14751291-8 2004 In the CeA, cocaine pre-exposure increased both CRH and CRH-BP mRNA expression 1 day post-treatment. Cocaine 12-19 corticotropin releasing hormone Rattus norvegicus 48-51 14751291-9 2004 In the dorsal BNST, cocaine pre-exposure elevated levels of CRH-BP, but not CRH, mRNA 3 days post-treatment. Cocaine 20-27 corticotropin releasing hormone Rattus norvegicus 60-63 12782395-2 2003 The present studies were undertaken to determine levels of CRH mRNA in the amygdala, and also in the hypothalamus, frontal cortex and brainstem after short-term (2 days) and intermediate-term (10 days) cocaine withdrawal (with continued saline injections) from chronic (14 days) "binge" pattern cocaine administration (3 x 15 mg/kg per day at hourly intervals). Cocaine 202-209 corticotropin releasing hormone Rattus norvegicus 59-62 12782395-4 2003 There was also a significant elevation of CRH mRNA levels in the amygdala, but not in the hypothalamus, frontal cortex or brainstem after 2-day cocaine withdrawal. Cocaine 144-151 corticotropin releasing hormone Rattus norvegicus 42-45 12782395-5 2003 A negative correlation between amygdalar CRH mRNA and plasma corticosterone levels was found in the 2-day cocaine withdrawn rats but not in control rats, suggesting that CRH neurons in the amygdala may be differentially responsive to glucocorticoids after chronic cocaine exposure and withdrawal. Cocaine 106-113 corticotropin releasing hormone Rattus norvegicus 41-44 12782395-5 2003 A negative correlation between amygdalar CRH mRNA and plasma corticosterone levels was found in the 2-day cocaine withdrawn rats but not in control rats, suggesting that CRH neurons in the amygdala may be differentially responsive to glucocorticoids after chronic cocaine exposure and withdrawal. Cocaine 106-113 corticotropin releasing hormone Rattus norvegicus 170-173 12782395-5 2003 A negative correlation between amygdalar CRH mRNA and plasma corticosterone levels was found in the 2-day cocaine withdrawn rats but not in control rats, suggesting that CRH neurons in the amygdala may be differentially responsive to glucocorticoids after chronic cocaine exposure and withdrawal. Cocaine 264-271 corticotropin releasing hormone Rattus norvegicus 41-44 12782395-5 2003 A negative correlation between amygdalar CRH mRNA and plasma corticosterone levels was found in the 2-day cocaine withdrawn rats but not in control rats, suggesting that CRH neurons in the amygdala may be differentially responsive to glucocorticoids after chronic cocaine exposure and withdrawal. Cocaine 264-271 corticotropin releasing hormone Rattus norvegicus 170-173