PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18325696-3	2008	During apoptosis induction by sanguinarine and chelerythrine, reactive oxygen species (ROS) was rapidly generated and DeltaPsi(mt) dissipated, while Bax, Bcl-2 and Bcl-X((L/S)) proteins" content in the mitochondrial fraction did not change significantly.	sanguinarine	30-42	BCL2 like 1	Homo sapiens	164-169	
17005319-6	2007	Further, sanguinarine-treatment to AsPC-1 and BxPC-3 cells resulted in a dose dependent (i) increase in pro-apoptotic Bax, Bid and Bak proteins; (ii) decrease in anti-apoptotic Bcl-2 and Bcl-X(L) proteins; and (iii) decrease in p53 with an increase in its phosphorylation.	sanguinarine	9-21	BCL2 like 1	Homo sapiens	187-195	
18925736-1	2008	Despite their structural similarities, the natural products chelerythrine ( 5) and sanguinarine ( 6) target different binding sites on the pro-survival Bcl-X L protein.	sanguinarine	83-95	BCL2 like 1	Homo sapiens	152-159	
17011577-0	2006	Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.	sanguinarine	18-30	BCL2 like 1	Homo sapiens	57-62	
16505117-5	2006	These responses on UVB and/or sanguinarine treatments were associated with (a) decrease in Bcl-2 and Bcl-X(L) and (b) increase in Bax, Bid, and Bak protein levels.	sanguinarine	30-42	BCL2 like 1	Homo sapiens	101-109