PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31982399-4 2020 17beta-HSD12 (presumably orthologous to salmon 17beta-HSD12L) has been detected in Nile tilapia; however, its enzymatic activity and specific ability to convert the DHP substrate 17alpha-hydroxyprogesterone (17OHP) have not been examined. dhp 165-168 hydroxysteroid 17-beta dehydrogenase 12 Homo sapiens 0-12 31982399-5 2020 This study aimed to determine whether CR/20beta-HSD or 17beta-HSD12 is responsible for DHP production during oocyte maturation in the Nile tilapia. dhp 87-90 hydroxysteroid 17-beta dehydrogenase 12 Homo sapiens 55-67 31982399-7 2020 HEK293T cells transfected with hsd17b12 exhibited a strong ability to convert exogenous 17OHP to DHP (73.8% yield). dhp 97-100 hydroxysteroid 17-beta dehydrogenase 12 Homo sapiens 31-39 31982399-14 2020 The present study strongly suggests that 17beta-HSD12, and not CR/20beta-HSD, is the 20beta-HSD responsible for DHP production by ovarian follicles during oocyte maturation in Nile tilapia. dhp 112-115 hydroxysteroid 17-beta dehydrogenase 12 Homo sapiens 41-53