PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29655979-1 2018 During the course of our research efforts to develop potent and selective AKT inhibitors, we discovered enatiomerically pure substituted dihydropyridopyrimidinones (DHP) as potent inhibitors of protein kinase B/AKT with excellent selectivity against ROCK2. dhp 165-168 Rho associated coiled-coil containing protein kinase 2 Homo sapiens 250-255