PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1092682-5	1975	The Michaelis constants determined for S-adenosyl-L-methionine and 7-keto-8-aminopelargonic acid were 0.20 mM and 1.2 muM, respectively.	S-Adenosylmethionine	39-62	latexin	Homo sapiens	118-121	
26974652-7	2016	The optimal concentrations of the cofactor S-adenosyl-L-methionine (SAM) and substrate 5-aminolevulinic acid (ALA) were also determined to be 200 muM and 5 mM, respectively, in a tandem-enzyme assay.	S-Adenosylmethionine	43-66	latexin	Homo sapiens	146-149	
27464505-9	2016	The inhibition study showed that, in the presence of SAM as methyl donor, Lomeguatrib, 5-Azacytidine, and 5-Aza-2"-deoxycytidine could inhibit the DNA MTase activity with IC50 values of 40.57 nM, 2.26 muM, and 0.48 muM, respectively.	S-Adenosylmethionine	53-56	latexin	Homo sapiens	201-204	
27464505-9	2016	The inhibition study showed that, in the presence of SAM as methyl donor, Lomeguatrib, 5-Azacytidine, and 5-Aza-2"-deoxycytidine could inhibit the DNA MTase activity with IC50 values of 40.57 nM, 2.26 muM, and 0.48 muM, respectively.	S-Adenosylmethionine	53-56	latexin	Homo sapiens	215-218	
26974652-7	2016	The optimal concentrations of the cofactor S-adenosyl-L-methionine (SAM) and substrate 5-aminolevulinic acid (ALA) were also determined to be 200 muM and 5 mM, respectively, in a tandem-enzyme assay.	S-Adenosylmethionine	68-71	latexin	Homo sapiens	146-149	
23030620-6	2012	Furthermore, the inhibition investigation demonstrated that, in the presence of 160 muM S-adenosyl-L-methionine as methyl donor, 5-aza-2"-deoxycytidine, procaine, epicatechin, and caffeic acid could inhibit the M. SssI MTase activity with the IC(50) values of 45.77, 410.3, 129.03, and 124.2 muM, respectively.	S-Adenosylmethionine	88-111	latexin	Homo sapiens	84-87	
23030620-6	2012	Furthermore, the inhibition investigation demonstrated that, in the presence of 160 muM S-adenosyl-L-methionine as methyl donor, 5-aza-2"-deoxycytidine, procaine, epicatechin, and caffeic acid could inhibit the M. SssI MTase activity with the IC(50) values of 45.77, 410.3, 129.03, and 124.2 muM, respectively.	S-Adenosylmethionine	88-111	latexin	Homo sapiens	292-295