PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28271477-4 2017 The structure of the 453 kDa heterooctameric PRMT5:MEP50 complex bound to an S-adenosylmethionine analog and a substrate peptide provides valuable insights into this intriguing target. S-Adenosylmethionine 79-97 WD repeat domain 77 Homo sapiens 51-56 23071334-5 2012 We have determined the crystal structure of human PRMT5 in complex with MEP50 (methylosome protein 50), bound to an S-adenosylmethionine analog and a peptide substrate derived from histone H4. S-Adenosylmethionine 116-136 WD repeat domain 77 Homo sapiens 72-77 23071334-5 2012 We have determined the crystal structure of human PRMT5 in complex with MEP50 (methylosome protein 50), bound to an S-adenosylmethionine analog and a peptide substrate derived from histone H4. S-Adenosylmethionine 116-136 WD repeat domain 77 Homo sapiens 79-101 29154828-0 2018 Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods. S-Adenosylmethionine 39-57 WD repeat domain 77 Homo sapiens 118-140