PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29379364-3	2018	S-adenosyl-l-methionine (SAM) is an important intermediate of folic acid pathway and acts as methyl donor and substrate for DNA (cytosine-5)-methyltransferase 3B (DNMT3B - EC 2.1.1.37) de novo methylation processes during embryogenesis.	S-Adenosylmethionine	0-23	DNA methyltransferase 3 beta	Homo sapiens	124-161	
30309036-2	2018	The methylation of DNA is regulated by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b) in the presence of S-adenosylmethionine (SAM), which serves as a methyl group donor.	S-Adenosylmethionine	109-129	DNA methyltransferase 3 beta	Homo sapiens	82-88	
30309036-2	2018	The methylation of DNA is regulated by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b) in the presence of S-adenosylmethionine (SAM), which serves as a methyl group donor.	S-Adenosylmethionine	131-134	DNA methyltransferase 3 beta	Homo sapiens	82-88	
29379364-3	2018	S-adenosyl-l-methionine (SAM) is an important intermediate of folic acid pathway and acts as methyl donor and substrate for DNA (cytosine-5)-methyltransferase 3B (DNMT3B - EC 2.1.1.37) de novo methylation processes during embryogenesis.	S-Adenosylmethionine	0-23	DNA methyltransferase 3 beta	Homo sapiens	163-169	
29379364-3	2018	S-adenosyl-l-methionine (SAM) is an important intermediate of folic acid pathway and acts as methyl donor and substrate for DNA (cytosine-5)-methyltransferase 3B (DNMT3B - EC 2.1.1.37) de novo methylation processes during embryogenesis.	S-Adenosylmethionine	25-28	DNA methyltransferase 3 beta	Homo sapiens	124-161	
29379364-3	2018	S-adenosyl-l-methionine (SAM) is an important intermediate of folic acid pathway and acts as methyl donor and substrate for DNA (cytosine-5)-methyltransferase 3B (DNMT3B - EC 2.1.1.37) de novo methylation processes during embryogenesis.	S-Adenosylmethionine	25-28	DNA methyltransferase 3 beta	Homo sapiens	163-169	
23957506-3	2013	We tested the hypothesis that plasma S-adenosylmethionine (SAM) level alone or in combination with genetic variation in DNA methyltransferases (DNMT1, DNMT3A and DNMT3B) was associated with global DNA methylation extent at long interspersed nucleotide element-1 (LINE-1) sequences.	S-Adenosylmethionine	37-57	DNA methyltransferase 3 beta	Homo sapiens	162-168	
25289094-1	2014	DNA methyltransferases (including DNMT1, DNMT3A and DNMT3B), catalyze the transfer of methyl groups from S-adenosyl-l-methionine to cytosine position 5; this methylation in promoter regions silences gene expression.	S-Adenosylmethionine	105-128	DNA methyltransferase 3 beta	Homo sapiens	52-58	
23957506-3	2013	We tested the hypothesis that plasma S-adenosylmethionine (SAM) level alone or in combination with genetic variation in DNA methyltransferases (DNMT1, DNMT3A and DNMT3B) was associated with global DNA methylation extent at long interspersed nucleotide element-1 (LINE-1) sequences.	S-Adenosylmethionine	59-62	DNA methyltransferase 3 beta	Homo sapiens	162-168	
21549127-4	2011	First, DNMT3B, unlike DNMT3A, requires a DNA cofactor in order to stably bind to S-adenosyl-l-methionine (SAM), suggesting that it proceeds according to an ordered catalytic scheme.	S-Adenosylmethionine	81-104	DNA methyltransferase 3 beta	Homo sapiens	7-13	
21839172-4	2011	Herein we report long (>100ns) molecular dynamics simulations for human DNMT3B bound to nanaomycin A with and without the presence of the cofactor S-adenosyl-L-methionine (SAM).	S-Adenosylmethionine	150-173	DNA methyltransferase 3 beta	Homo sapiens	75-81	
21839172-4	2011	Herein we report long (>100ns) molecular dynamics simulations for human DNMT3B bound to nanaomycin A with and without the presence of the cofactor S-adenosyl-L-methionine (SAM).	S-Adenosylmethionine	175-178	DNA methyltransferase 3 beta	Homo sapiens	75-81