PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23051747-8 2012 Here we demonstrate that GSK126, a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity, decreases global H3K27me3 levels and reactivates silenced PRC2 target genes. S-Adenosylmethionine 63-82 enhancer of zeste 2 polycomb repressive complex 2 subunit Mus musculus 124-128