PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19565184-0	2009	S-adenosylmethionine and S-adenosylhomocysteine levels in the aging brain of APP/PS1 Alzheimer mice.	S-Adenosylmethionine	0-20	presenilin 1	Mus musculus	81-84	
22221883-5	2012	We found that S-adenosylmethionine reduced amyloid production, increased spatial memory in TgCRND8 mice and inhibited the upregulation of B vitamin deficiency-induced PSEN1 and BACE1 expression and Tau phosphorylation in TgCRND8 and wild-type mice.	S-Adenosylmethionine	14-34	presenilin 1	Mus musculus	167-172	
17183144-8	2006	Prior studies demonstrate that impaired DNA methylation resulting from a deficiency in S-adenosylmethionine (SAM, which is rapidly depleted following folate deprivation) leads to PS-1 overexpression, and that direct supplementation with SAM attenuates PS-1 overexpression.	S-Adenosylmethionine	87-107	presenilin 1	Mus musculus	179-183	
17183144-8	2006	Prior studies demonstrate that impaired DNA methylation resulting from a deficiency in S-adenosylmethionine (SAM, which is rapidly depleted following folate deprivation) leads to PS-1 overexpression, and that direct supplementation with SAM attenuates PS-1 overexpression.	S-Adenosylmethionine	109-112	presenilin 1	Mus musculus	179-183	
17183144-8	2006	Prior studies demonstrate that impaired DNA methylation resulting from a deficiency in S-adenosylmethionine (SAM, which is rapidly depleted following folate deprivation) leads to PS-1 overexpression, and that direct supplementation with SAM attenuates PS-1 overexpression.	S-Adenosylmethionine	109-112	presenilin 1	Mus musculus	252-256