PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11984522-7 2002 We have studied the modulation of hepatocyte growth factor-induced proliferation by NO through the regulation of S-adenosylmethionine levels. S-Adenosylmethionine 113-133 hepatocyte growth factor Homo sapiens 34-58 11984522-11 2002 Accordingly, we found that S-adenosylmethionine inhibits hepatocyte growth factor-induced cyclin D1 and D2 expression, activator protein 1 induction, and hepatocyte proliferation. S-Adenosylmethionine 27-47 hepatocyte growth factor Homo sapiens 57-81 11984522-12 2002 CONCLUSIONS: Together our findings indicate that NO may switch hepatocytes into a hepatocyte growth factor-responsive state through the down-regulation of S-adenosylmethionine levels. S-Adenosylmethionine 155-175 hepatocyte growth factor Homo sapiens 82-106