PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33170152-0 2020 S-adenosylmethionine administration inhibits levodopa-induced vascular endothelial growth factor-A expression. S-Adenosylmethionine 0-20 vascular endothelial growth factor A Homo sapiens 62-98 33170152-2 2020 RESULTS: S-adenosylmethionine and levodopa had opposite effects on the protein stability of vascular endothelial growth factor-A. S-Adenosylmethionine 9-29 vascular endothelial growth factor A Homo sapiens 92-128 33170152-7 2020 S-adenosylmethionine could be fitted into the predicted docking pocket in the crystal structure of vascular endothelial growth factor-A, enhancing its acetylation level and reducing half-life. S-Adenosylmethionine 0-20 vascular endothelial growth factor A Homo sapiens 99-135 33170152-8 2020 CONCLUSIONS: These observations suggested that methyl donor S-adenosylmethionine could act as a potential agent against vascular endothelial growth factor-A-related diseases induced by levodopa treatment. S-Adenosylmethionine 60-80 vascular endothelial growth factor A Homo sapiens 120-156 33170152-9 2020 METHODS: We performed in vitro cytological analyses to assess whether S-adenosylmethionine intake could influence levodopa-induced vascular endothelial growth factor-A expression in human umbilical vein endothelial cells. S-Adenosylmethionine 70-90 vascular endothelial growth factor A Homo sapiens 131-167