PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15185841-0	2004	Involvement of NF-kappaB and c-myc signaling pathways in the apoptosis of HL-60 cells induced by alkaloids of Tripterygium hypoglaucum (levl.)	Alkaloids	97-106	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	29-34	
25547724-0	2014	Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations.	Alkaloids	51-59	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	107-112	
28686226-5	2017	Both in vitro and in vivo, lipid-lowering alkaloid berberine (BBR) exhibited an anti-lymphoma activity through inhibiting MYC-driven downstream PCYT1A expression and inducing mitophagy-dependent necroptosis.	Alkaloids	42-50	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	122-125	
25712523-0	2015	Quadruplex forming promoter region of c-myc oncogene as a potential target for a telomerase inhibitory plant alkaloid, chelerythrine.	Alkaloids	109-117	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	38-43	
22480315-0	2012	The interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids.	Alkaloids	74-83	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	37-42	
21156346-7	2011	We show that both, an aqueous and an alkaloid-enriched extract specifically inhibit Wnt-signaling activity in HeLa, HCT116 and SW480 cancer cells resulting in reduced expression of the Wnt-target gene: c-Myc.	Alkaloids	37-45	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	202-207