PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25712523-0 2015 Quadruplex forming promoter region of c-myc oncogene as a potential target for a telomerase inhibitory plant alkaloid, chelerythrine. Alkaloids 109-117 MYC proto-oncogene, bHLH transcription factor Homo sapiens 38-43 28686226-5 2017 Both in vitro and in vivo, lipid-lowering alkaloid berberine (BBR) exhibited an anti-lymphoma activity through inhibiting MYC-driven downstream PCYT1A expression and inducing mitophagy-dependent necroptosis. Alkaloids 42-50 MYC proto-oncogene, bHLH transcription factor Homo sapiens 122-125 22480315-0 2012 The interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids. Alkaloids 74-83 MYC proto-oncogene, bHLH transcription factor Homo sapiens 37-42 25547724-0 2014 Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations. Alkaloids 51-59 MYC proto-oncogene, bHLH transcription factor Homo sapiens 107-112 21156346-7 2011 We show that both, an aqueous and an alkaloid-enriched extract specifically inhibit Wnt-signaling activity in HeLa, HCT116 and SW480 cancer cells resulting in reduced expression of the Wnt-target gene: c-Myc. Alkaloids 37-45 MYC proto-oncogene, bHLH transcription factor Homo sapiens 202-207 15185841-0 2004 Involvement of NF-kappaB and c-myc signaling pathways in the apoptosis of HL-60 cells induced by alkaloids of Tripterygium hypoglaucum (levl.) Alkaloids 97-106 MYC proto-oncogene, bHLH transcription factor Homo sapiens 29-34