PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22390216-1	2012	The antineoplastic alkaloid ellipticine is a prodrug, whose pharmacological efficiency is dependent on its cytochrome P450 (P450)- and/or peroxidase-mediated activation in target tissues.	Alkaloids	19-27	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	124-148	
8055971-2	1994	The interaction between rat and human liver cytochromes P450 with a series of lysergic acid derivatives and ergopeptide alkaloids was studied by difference visible spectroscopy.	Alkaloids	120-129	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	56-60	
11469727-1	2001	Cytochrome P450 (P450) enzymes play major roles in the metabolism of drugs, carcinogens, steroids, eicosanoids, alkaloids, pesticides, and other important xenobiotics, as well as chemicals normally endogenous to the body.	Alkaloids	112-121	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	0-21	
35230092-1	2022	Intramolecular phenol coupling reactions of alkaloids can lead to active metabolites catalyzed by the mammalian cytochrome P450 enzyme (P450); however, the mechanistic knowledge of such an "unusual" process is lacking.	Alkaloids	44-53	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	135-141