PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15848192-1	2005	In this study, the human cytochrome P450 (CYP) 2A6 was used in order to modify the alkaloid production of tobacco plants.	Alkaloids	83-91	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	25-50	
14757175-0	2004	Nicotine-related alkaloids and metabolites as inhibitors of human cytochrome P-450 2A6.	Alkaloids	17-26	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	66-86	
14757175-3	2004	The tobacco alkaloids 2,3"-bipyridyl (7.7 microM) and S-(-)-anabasine (5.4 microM), were somewhat less potent compared with S-(-)-nicotine or S-(-)-anatabine in inhibition of human CYP2A6.	Alkaloids	12-21	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	181-187	
14757175-6	2004	The potency of the mechanism-based CYP2A6 inhibitors suggests that, for smokers, modulation of CYP2A6 may be greater than that predicted on the basis of serum concentration of these alkaloids.	Alkaloids	182-191	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	35-41	
10781881-3	2000	CYP2A6 is a major contributor to the oxidative metabolism of nicotine and cotinine, and it also contributes, to a larger or smaller extent, to the metabolism of a few pharmaceuticals (e.g. fadrozole), nitrosamines, other carcinogens (e.g. aflatoxin B1) and a number of coumarin-type alkaloids.	Alkaloids	283-292	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	0-6