PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7808368-4 1994 The existence of drugs (calcium blockers, cyclosporine, tamoxifen, reserpine, quinidine) able to bind themselves to gp170 and to paralyze its activity in vitro is well known. Reserpine 67-76 ATP binding cassette subfamily B member 1 Homo sapiens 116-121 7476894-2 1995 Because some P-gp inhibitors (e.g., verapamil and nifedipine) can increase mdr1 and P-gp expression in human colon carcinoma cell lines, we used our reserpine/yohimbine analogues to determine whether there was a structural requirement for this induction. Reserpine 149-158 ATP binding cassette subfamily B member 1 Homo sapiens 13-17 7476894-2 1995 Because some P-gp inhibitors (e.g., verapamil and nifedipine) can increase mdr1 and P-gp expression in human colon carcinoma cell lines, we used our reserpine/yohimbine analogues to determine whether there was a structural requirement for this induction. Reserpine 149-158 ATP binding cassette subfamily B member 1 Homo sapiens 75-79 7476894-2 1995 Because some P-gp inhibitors (e.g., verapamil and nifedipine) can increase mdr1 and P-gp expression in human colon carcinoma cell lines, we used our reserpine/yohimbine analogues to determine whether there was a structural requirement for this induction. Reserpine 149-158 ATP binding cassette subfamily B member 1 Homo sapiens 84-88 7476894-3 1995 We found that 10 microM reserpine increased both mdr1 and P-gp expression by 4-10-fold in 48 hr in a human colon carcinoma cell line that expresses moderate levels of mdr1 (LS180-Ad50) but not in several other cell lines that expressed no mdr1. Reserpine 24-33 ATP binding cassette subfamily B member 1 Homo sapiens 49-53 7476894-3 1995 We found that 10 microM reserpine increased both mdr1 and P-gp expression by 4-10-fold in 48 hr in a human colon carcinoma cell line that expresses moderate levels of mdr1 (LS180-Ad50) but not in several other cell lines that expressed no mdr1. Reserpine 24-33 ATP binding cassette subfamily B member 1 Homo sapiens 58-62 7476894-3 1995 We found that 10 microM reserpine increased both mdr1 and P-gp expression by 4-10-fold in 48 hr in a human colon carcinoma cell line that expresses moderate levels of mdr1 (LS180-Ad50) but not in several other cell lines that expressed no mdr1. Reserpine 24-33 ATP binding cassette subfamily B member 1 Homo sapiens 167-171 7476894-3 1995 We found that 10 microM reserpine increased both mdr1 and P-gp expression by 4-10-fold in 48 hr in a human colon carcinoma cell line that expresses moderate levels of mdr1 (LS180-Ad50) but not in several other cell lines that expressed no mdr1. Reserpine 24-33 ATP binding cassette subfamily B member 1 Homo sapiens 167-171 7720780-5 1995 The cellular accumulation of [14C]pristinamycin IA was very low and was increased by P-glycoprotein inhibitors (verapamil, chlorpromazine and reserpine). Reserpine 142-151 ATP binding cassette subfamily B member 1 Homo sapiens 85-99 9111066-1 1997 The P-glycoprotein (Pgp) reversing agent, reserpine, induces MDR1 mRNA and PGP protein in human colon carcinoma cells (Schuetz, E. G., Beck, W. T., and Schuetz, J. D. (1996) Mol. Reserpine 42-51 ATP binding cassette subfamily B member 1 Homo sapiens 4-18 9111066-1 1997 The P-glycoprotein (Pgp) reversing agent, reserpine, induces MDR1 mRNA and PGP protein in human colon carcinoma cells (Schuetz, E. G., Beck, W. T., and Schuetz, J. D. (1996) Mol. Reserpine 42-51 ATP binding cassette subfamily B member 1 Homo sapiens 20-23 9111066-1 1997 The P-glycoprotein (Pgp) reversing agent, reserpine, induces MDR1 mRNA and PGP protein in human colon carcinoma cells (Schuetz, E. G., Beck, W. T., and Schuetz, J. D. (1996) Mol. Reserpine 42-51 ATP binding cassette subfamily B member 1 Homo sapiens 61-65 8855237-6 1996 LmrA and MDR1 extrude a similar spectrum of amphiphilic cationic compounds, and the activity of both systems is reversed by reserpine and verapamil. Reserpine 124-133 ATP binding cassette subfamily B member 1 Homo sapiens 9-13 8624264-5 1996 This resistance could be substantially reduced by inclusion of the P-gp inhibitor reserpine. Reserpine 82-91 ATP binding cassette subfamily B member 1 Homo sapiens 67-71 8632764-3 1996 P-glycoprotein and CYP3A4 were constitutively expressed in both LS180/AD50 and LS180/WT cells, and both proteins were up-regulated after treatment with many drugs, including rifampicin, phenobarbital, clotrimazole, reserpine, and isosafrole. Reserpine 215-224 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 7476894-0 1995 A structure-function relationship among reserpine and yohimbine analogues in their ability to increase expression of mdr1 and P-glycoprotein in a human colon carcinoma cell line. Reserpine 40-49 ATP binding cassette subfamily B member 1 Homo sapiens 117-121 7476894-0 1995 A structure-function relationship among reserpine and yohimbine analogues in their ability to increase expression of mdr1 and P-glycoprotein in a human colon carcinoma cell line. Reserpine 40-49 ATP binding cassette subfamily B member 1 Homo sapiens 126-140 7476894-1 1995 We previously showed that there is a structure-function relationship among reserpine and yohimbine analogues in their ability to inhibit the function of P-glycoprotein (P-gp) and reverse multidrug resistance (MDR). Reserpine 75-84 ATP binding cassette subfamily B member 1 Homo sapiens 153-167 7476894-1 1995 We previously showed that there is a structure-function relationship among reserpine and yohimbine analogues in their ability to inhibit the function of P-glycoprotein (P-gp) and reverse multidrug resistance (MDR). Reserpine 75-84 ATP binding cassette subfamily B member 1 Homo sapiens 169-173 7945455-4 1994 The polarized transport of vinblastine in the basolateral to apical direction was temperature and energy dependent, and was reduced by P-glycoprotein inhibitors such as verapamil, chlorpromazine and reserpine. Reserpine 199-208 ATP binding cassette subfamily B member 1 Homo sapiens 135-149 7945455-7 1994 This polarized transport was inhibited by verapamil, chlorpromazine and reserpine, thus demonstrating that docetaxel is a substrate of P-glycoprotein. Reserpine 72-81 ATP binding cassette subfamily B member 1 Homo sapiens 135-149 34848472-3 2021 Considering that reserpine (P-gp inhibitor) plays a regulatory role in patients with high blood pressure, we investigated the effect of low doses of 27 blood pressure-regulating drugs on VIC-resistant KBV20C cells. Reserpine 17-26 ATP binding cassette subfamily B member 1 Homo sapiens 28-32 1967551-7 1990 Modulators of Pgp-MDR also compete with LU-49888 for binding to Pgp: verapamil (82%), diltiazem (73%), quinidine (91%), reserpine (91%), rescinnamine (88%), and trimethoxybenzoylyohimbine (89%). Reserpine 120-129 ATP binding cassette subfamily B member 1 Homo sapiens 14-17 1983720-3 1990 Anti-cancer drug sensitivity is restored by addition of other drugs (i.e., verapamil, reserpine) which are also P-glycoprotein substrates. Reserpine 86-95 ATP binding cassette subfamily B member 1 Homo sapiens 112-126 34848472-10 2021 We found that reserpine had the highest P-gp-inhibitory activity, indicating that eribulin- or VIC-reserpine sensitization involves the P-gp inhibitory effects of reserpine. Reserpine 14-23 ATP binding cassette subfamily B member 1 Homo sapiens 40-44 34848472-10 2021 We found that reserpine had the highest P-gp-inhibitory activity, indicating that eribulin- or VIC-reserpine sensitization involves the P-gp inhibitory effects of reserpine. Reserpine 14-23 ATP binding cassette subfamily B member 1 Homo sapiens 136-140 34848472-10 2021 We found that reserpine had the highest P-gp-inhibitory activity, indicating that eribulin- or VIC-reserpine sensitization involves the P-gp inhibitory effects of reserpine. Reserpine 99-108 ATP binding cassette subfamily B member 1 Homo sapiens 136-140 34848472-10 2021 We found that reserpine had the highest P-gp-inhibitory activity, indicating that eribulin- or VIC-reserpine sensitization involves the P-gp inhibitory effects of reserpine. Reserpine 163-172 ATP binding cassette subfamily B member 1 Homo sapiens 40-44 34848472-10 2021 We found that reserpine had the highest P-gp-inhibitory activity, indicating that eribulin- or VIC-reserpine sensitization involves the P-gp inhibitory effects of reserpine. Reserpine 163-172 ATP binding cassette subfamily B member 1 Homo sapiens 136-140