PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2325165-10 1990 DBH mRNA levels were induced in vivo in rat adrenals upon treatment with reserpine. Reserpine 73-82 dopamine beta-hydroxylase Rattus norvegicus 0-3 7984052-1 1994 Reserpine treatment was used to examine whether short- and long-term neural stimulation regulates rat adrenal medullary dopamine beta-hydroxylase (DBH, EC 1.14.17.1) through transcriptional activation and to examine the extent of coordinate control of DBH and phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28). Reserpine 0-9 dopamine beta-hydroxylase Rattus norvegicus 120-145 7984052-1 1994 Reserpine treatment was used to examine whether short- and long-term neural stimulation regulates rat adrenal medullary dopamine beta-hydroxylase (DBH, EC 1.14.17.1) through transcriptional activation and to examine the extent of coordinate control of DBH and phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28). Reserpine 0-9 dopamine beta-hydroxylase Rattus norvegicus 147-150 7984052-1 1994 Reserpine treatment was used to examine whether short- and long-term neural stimulation regulates rat adrenal medullary dopamine beta-hydroxylase (DBH, EC 1.14.17.1) through transcriptional activation and to examine the extent of coordinate control of DBH and phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28). Reserpine 0-9 dopamine beta-hydroxylase Rattus norvegicus 252-255 7984052-5 1994 Even though DBH mRNA is elevated 6 h after a single injection of reserpine, DBH activity does not change in parallel. Reserpine 65-74 dopamine beta-hydroxylase Rattus norvegicus 12-15 7984052-7 1994 In contrast, chronic reserpine treatment concomitantly increases DBH activity and mRNA. Reserpine 21-30 dopamine beta-hydroxylase Rattus norvegicus 65-68 956830-0 1976 Increased synthesis of dopamine beta-hydroxylase in cultured rat adrenal medullae after in vivo administration of reserpine. Reserpine 114-123 dopamine beta-hydroxylase Rattus norvegicus 23-48 3221059-2 1988 The extent of dopamine beta-hydroxylase induction elicited by reserpine was measured in young rats rendered hypothyroid from birth and in controls. Reserpine 62-71 dopamine beta-hydroxylase Rattus norvegicus 14-39 2819772-5 1987 We can conclude that nervous stimulation of the adrenal medulla (by insulin and reserpine) induces the synthesis of enkephalins, dopamine beta-hydroxylase, the amine carrier and chromogranin B whereas the level of chromogranin A apparently depends on corticosteroids. Reserpine 80-89 dopamine beta-hydroxylase Rattus norvegicus 129-154 2938024-1 1986 The systemic administration of reserpine to rats increases adrenal dopamine beta-hydroxylase activity, but is without significant effect on the Km(tyramine). Reserpine 31-40 dopamine beta-hydroxylase Rattus norvegicus 67-92 2938024-5 1986 p-Chlorophenylalanine (intraperitoneal) or 5,7-dihydroxytryptamine (intracerebroventricular or injected into the medial raphe nucleus) increases the effect of reserpine, but the use of a catecholamine-depleting agent with reserpine does not alter the increase of adrenal dopamine beta-hydroxylase obtained with reserpine alone. Reserpine 159-168 dopamine beta-hydroxylase Rattus norvegicus 271-296 19604771-0 1976 Reserpine-induced changes in dopamine-beta-hydroxylase activity in the terminal projections of the nucleus locus coeruleus. Reserpine 0-9 dopamine beta-hydroxylase Rattus norvegicus 29-54 19604771-3 1976 In accordance with previous reports, reserpine significantly increased DBH activity in dorsal pons 1 and 2 weeks after reserpine. Reserpine 37-46 dopamine beta-hydroxylase Rattus norvegicus 71-74 19604771-3 1976 In accordance with previous reports, reserpine significantly increased DBH activity in dorsal pons 1 and 2 weeks after reserpine. Reserpine 119-128 dopamine beta-hydroxylase Rattus norvegicus 71-74 19604771-5 1976 Induction of DBH in the locus coeruleus is not, therefore, subsequently reflected in an overall increase in enzyme activity in the terminals arising from this nucleus; on the contrary, reserpine produces long-term decreases in DBH activity in these regions. Reserpine 185-194 dopamine beta-hydroxylase Rattus norvegicus 227-230 2869825-10 1986 After local vinblastine-treatment of the lumbar sympathetic ganglia the amounts of DBH-IR and TH-IR in the perikarya were markedly lower in reserpine treated rats than in controls, probably due to a decreased perikaryal synthesis of these two enzymes. Reserpine 140-149 dopamine beta-hydroxylase Rattus norvegicus 83-86 3940292-1 1986 The effect of reserpine on the activity of dopamine beta-hydroxylase (DBH) in the adrenal gland of the rat was determined following electrolytic lesion of the dorsal raphe nucleus (DRN) or medial raphe nucleus (MRN). Reserpine 14-23 dopamine beta-hydroxylase Rattus norvegicus 43-68 3940292-1 1986 The effect of reserpine on the activity of dopamine beta-hydroxylase (DBH) in the adrenal gland of the rat was determined following electrolytic lesion of the dorsal raphe nucleus (DRN) or medial raphe nucleus (MRN). Reserpine 14-23 dopamine beta-hydroxylase Rattus norvegicus 70-73 6162666-0 1981 Reserpine effect on the axonal transport of dopamine-beta-hydroxylase and tyrosine hydroxylase in rat brain. Reserpine 0-9 dopamine beta-hydroxylase Rattus norvegicus 44-69 12170592-3 1976 In cultured adrenal medullae, induction of dopamine beta-hydroxylase initiated in vivo by administration of reserpine affected both soluble and membrane-bound pools of dopamine beta-hydroxylase to a similar extent after pulse-labelling for 1 or 3 h. The half-lives of dopamine beta-hydroxylase, which amounted to 6 h for the cytosol, 7.5 h for the soluble vesicular and 32 h for the membrane-bound vesicular pools were not altered by pretreatment with reserpine. Reserpine 108-117 dopamine beta-hydroxylase Rattus norvegicus 43-68 12170592-3 1976 In cultured adrenal medullae, induction of dopamine beta-hydroxylase initiated in vivo by administration of reserpine affected both soluble and membrane-bound pools of dopamine beta-hydroxylase to a similar extent after pulse-labelling for 1 or 3 h. The half-lives of dopamine beta-hydroxylase, which amounted to 6 h for the cytosol, 7.5 h for the soluble vesicular and 32 h for the membrane-bound vesicular pools were not altered by pretreatment with reserpine. Reserpine 108-117 dopamine beta-hydroxylase Rattus norvegicus 168-193 12170592-3 1976 In cultured adrenal medullae, induction of dopamine beta-hydroxylase initiated in vivo by administration of reserpine affected both soluble and membrane-bound pools of dopamine beta-hydroxylase to a similar extent after pulse-labelling for 1 or 3 h. The half-lives of dopamine beta-hydroxylase, which amounted to 6 h for the cytosol, 7.5 h for the soluble vesicular and 32 h for the membrane-bound vesicular pools were not altered by pretreatment with reserpine. Reserpine 108-117 dopamine beta-hydroxylase Rattus norvegicus 168-193 12170592-3 1976 In cultured adrenal medullae, induction of dopamine beta-hydroxylase initiated in vivo by administration of reserpine affected both soluble and membrane-bound pools of dopamine beta-hydroxylase to a similar extent after pulse-labelling for 1 or 3 h. The half-lives of dopamine beta-hydroxylase, which amounted to 6 h for the cytosol, 7.5 h for the soluble vesicular and 32 h for the membrane-bound vesicular pools were not altered by pretreatment with reserpine. Reserpine 452-461 dopamine beta-hydroxylase Rattus norvegicus 43-68 180451-0 1976 Effect of dopamine-beta-hydroxylase inhibitors on thermoregulation in reserpine-treated rats. Reserpine 70-79 dopamine beta-hydroxylase Rattus norvegicus 10-35 50436-4 1975 Chronic reserpine treatment (2.5 mg/kg on alternate days) increased plasma DBH after 2 and 5 days, whereas vinblastine (3 mg/kg) caused a progressive fall in enzyme activity in plasma over the same time period. Reserpine 8-17 dopamine beta-hydroxylase Rattus norvegicus 75-78 235542-2 1975 Activation of the splanchnic nerves to the adrenal medulla by reserpine induces the synthesis of dopamine beta-hydroxylase without altering the rate of enzyme degradation. Reserpine 62-71 dopamine beta-hydroxylase Rattus norvegicus 97-122 1137729-4 1975 Reserpine also produced a larger increase in SHR catecholamines and dopamine beta-hydroxylase several days later; chlorisondamine pretreatment did not prevent the increases, although it did slightly slow the increases. Reserpine 0-9 dopamine beta-hydroxylase Rattus norvegicus 68-93 1171813-13 1975 Potentiation with reserpine may depend on a post-synaptic mechanism and increase in dopamine-beta-hydroxylase activity. Reserpine 18-27 dopamine beta-hydroxylase Rattus norvegicus 84-109 4317916-2 1970 The administration of reserpine leads to an increase in dopamine-beta-hydroxylase activity in the rat adrenal, heart, salivary gland, and in sympathetic ganglia. Reserpine 22-31 dopamine beta-hydroxylase Rattus norvegicus 56-81