PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2393551-5 1990 If U-13C-glucose is used and recycling of isotope not quantitated, the resulting calculated value for Ra glucose will represent the rate of production from non-recycled carbons, plus some recycled carbons, due to potential dilution of 13C in the oxaloacetate pool and some loss of 13C in the PEPCK reaction. Oxaloacetic Acid 246-258 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 292-297 24425216-14 1977 Studies with 3-mercaptopicolinic acid, a specific inhibitor of PEP-CK, have indicated that most (about 70%) of the OAA formed from aspartate is decarboxylated through the chloroplastic PEP-CK and the remaining (about 30%) OAA through the mitochondrial NAD-ME. Oxaloacetic Acid 115-118 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 63-69 34584739-3 2021 To demonstrate the capabilities of MMQX, the conversion of oxaloacetic acid to phosphoenolpyruvate by phosphoenolpyruvate carboxy-kinase (PEPCK) is observed with a time resolution of 40 ms. By lowering the entry barrier to time-resolved crystallography, MMQX should enable a broad expansion in structural studies of protein dynamics. Oxaloacetic Acid 59-75 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 102-136 34584739-3 2021 To demonstrate the capabilities of MMQX, the conversion of oxaloacetic acid to phosphoenolpyruvate by phosphoenolpyruvate carboxy-kinase (PEPCK) is observed with a time resolution of 40 ms. By lowering the entry barrier to time-resolved crystallography, MMQX should enable a broad expansion in structural studies of protein dynamics. Oxaloacetic Acid 59-75 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 138-143 24425216-11 1977 Part of the OAA may be converted to malate and decarboxylated through NAD-ME, and part may be transported to the chloroplasts for decarboxylation through PEP-CK localized in the chloroplasts. Oxaloacetic Acid 12-15 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 154-160 24425216-14 1977 Studies with 3-mercaptopicolinic acid, a specific inhibitor of PEP-CK, have indicated that most (about 70%) of the OAA formed from aspartate is decarboxylated through the chloroplastic PEP-CK and the remaining (about 30%) OAA through the mitochondrial NAD-ME. Oxaloacetic Acid 115-118 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 185-191 24425216-14 1977 Studies with 3-mercaptopicolinic acid, a specific inhibitor of PEP-CK, have indicated that most (about 70%) of the OAA formed from aspartate is decarboxylated through the chloroplastic PEP-CK and the remaining (about 30%) OAA through the mitochondrial NAD-ME. Oxaloacetic Acid 222-225 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 63-69 28166201-3 2017 Here we show that mitochondrial phosphoenolpyruvate carboxykinase (PCK2), the hub molecule linking tricarboxylic acid (TCA) cycle, glycolysis and gluconeogenesis by conversion of mitochondrial oxaloacetate (OAA) to phosphoenolpyruvate, regulates glucose carbon flow direction in stem-like cells that repopulate tumors (tumor-repopulating cells (TRCs)). Oxaloacetic Acid 193-205 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 67-71 29262588-4 2017 Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), which is encoded by PCK2, catalyzes the conversion of oxaloacetate to phosphoenolpyruvate. Oxaloacetic Acid 113-125 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 49-56 29262588-4 2017 Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), which is encoded by PCK2, catalyzes the conversion of oxaloacetate to phosphoenolpyruvate. Oxaloacetic Acid 113-125 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 79-83 28166201-3 2017 Here we show that mitochondrial phosphoenolpyruvate carboxykinase (PCK2), the hub molecule linking tricarboxylic acid (TCA) cycle, glycolysis and gluconeogenesis by conversion of mitochondrial oxaloacetate (OAA) to phosphoenolpyruvate, regulates glucose carbon flow direction in stem-like cells that repopulate tumors (tumor-repopulating cells (TRCs)). Oxaloacetic Acid 207-210 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 67-71 24973213-1 2014 Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), encoded by the nuclear PCK2 gene, links TCA cycle intermediates and glycolytic pools through the conversion of mitochondrial oxaloacetate into phosphoenolpyruvate. Oxaloacetic Acid 184-196 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 49-56 26269598-1 2015 Phosphoenolpyruvate carboxykinase (PEPCK) is one of the pivotal enzymes that regulates the carbon flow of the central metabolism by fixing CO2 to phosphoenolpyruvate (PEP) to produce oxaloacetate or vice versa. Oxaloacetic Acid 183-195 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 35-40 27780757-4 2017 In this work we hypothesized that the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) could be improved by a controlled expression of the human mitochondrial GTP-dependent PEP carboxykinase. Oxaloacetic Acid 52-64 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 186-203 27780757-4 2017 In this work we hypothesized that the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) could be improved by a controlled expression of the human mitochondrial GTP-dependent PEP carboxykinase. Oxaloacetic Acid 66-69 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 186-203 24973213-1 2014 Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), encoded by the nuclear PCK2 gene, links TCA cycle intermediates and glycolytic pools through the conversion of mitochondrial oxaloacetate into phosphoenolpyruvate. Oxaloacetic Acid 184-196 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 82-86 11551200-1 2001 The enzyme phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the reversible conversion of oxalacetate and GTP to phosphoenolpyruvate (PEP), GDP, and CO2. Oxaloacetic Acid 92-103 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 11-44 11551200-1 2001 The enzyme phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the reversible conversion of oxalacetate and GTP to phosphoenolpyruvate (PEP), GDP, and CO2. Oxaloacetic Acid 92-103 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 46-51 23624997-1 2013 The interactions between oxaloacetic (OAA) and phosphoenolpyruvic carboxykinase (PEPCK) binding pocket in the presence and absence of hydrazine were carried out using quantum chemical calculations, based on the two-layered ONIOM (ONIOM2) approach. Oxaloacetic Acid 38-41 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 47-79 23624997-1 2013 The interactions between oxaloacetic (OAA) and phosphoenolpyruvic carboxykinase (PEPCK) binding pocket in the presence and absence of hydrazine were carried out using quantum chemical calculations, based on the two-layered ONIOM (ONIOM2) approach. Oxaloacetic Acid 38-41 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 81-86