PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32651957-5 2020 These allele-specific changes in transcriptional regulation lead to increased expression of gluconeogenesis-related genes (PCK1, G6PC and PPARGC1A) and their downstream metabolites (oxaloacetate and beta-D-fructose 2,6-bisphosphate). Oxaloacetic Acid 182-194 glucose-6-phosphatase catalytic subunit 1 Homo sapiens 129-133 2173703-0 1990 The liver glucose-6-phosphatase of intact microsomes is inhibited and displays sigmoid kinetics in the presence of alpha-ketoglutarate-magnesium and oxaloacetate-magnesium chelates. Oxaloacetic Acid 149-161 glucose-6-phosphatase catalytic subunit 1 Homo sapiens 10-31 2173703-4 1990 In this work, we report that, when complexed with Mg2+, two endogenous dicarboxylic keto acids (alpha-ketoglutarate (alpha-KG) and oxaloacetate (OAA] inhibit the glucose-6-phosphatase activity at low concentrations of substrate. Oxaloacetic Acid 131-143 glucose-6-phosphatase catalytic subunit 1 Homo sapiens 162-183