PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35359022-0 2022 Therapeutic Potential of Isorhamnetin following Acetaminophen-Induced Hepatotoxicity through Targeting NLRP3/NF-kappaB/Nrf2. 3-methylquercetin 25-37 NLR family, pyrin domain containing 3 Mus musculus 103-108 35359022-9 2022 These findings show protective effect of isorhamnetin against acetaminophen-induced liver injury through reducing oxidative stress, inflammation, and pyroptosis which is attributed to its regulation of NF-kB, Nrf2, NLRP3, and sirtuin 1. 3-methylquercetin 41-53 NLR family, pyrin domain containing 3 Mus musculus 215-220 35359022-7 2022 Isorhamnetin at the higher dose of 100 mg/kg significantly lowered serum levels of ALT, ALP, and AST in addition to reduction of ROS, TBARS, IL-6, TNFalpha, NF-kB, NLRP3, caspase 1, and MPO and significantly prevented reduction of GSH, SOD activity, sirtuin 1, and Nrf2. 3-methylquercetin 0-12 NLR family, pyrin domain containing 3 Mus musculus 164-169