PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11483407-4	2001	Tyrosine kinase inhibitors (genistein or tyrphostin 23) or phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor (D 609) attenuated TNF-alpha-induced ICAM-1 expression.	Tyrphostins	41-51	tumor necrosis factor	Homo sapiens	142-151	
11483407-11	2001	NF-kappaB DNA-protein binding and ICAM-1 promoter activity were enhanced by TNF-alpha and these effects were inhibited by D 609, calphostin C, or tyrphostin 23, but not by PD 98059 or SB 203580.	Tyrphostins	146-156	tumor necrosis factor	Homo sapiens	76-85	
7927986-3	1994	In addition, NLD and zymosan induced TNF alpha secretion which was impaired by a PTK inhibitor, tyrphostin.	Tyrphostins	96-106	tumor necrosis factor	Homo sapiens	37-46	
8937718-4	1996	In this study we have investigated the effects of the tyrosine kinase inhibitors, ST638, tyrphostin AG 1288 and genistein, on TNF alpha-induced ICAM-1 expression in human alveolar epithelial (A549) and vascular endothelial (EAhy926) cell lines and also normal human lung microvascular endothelial cells (HLMVEC).	Tyrphostins	89-99	tumor necrosis factor	Homo sapiens	126-135	
8537661-3	1996	Of 10 substances tested, only the protein tyrosine kinase inhibitor tyrphostin AG 126 discriminated significantly between PG and LPS: TNF-alpha release induced by PG, but not by LPS, was dose-dependently suppressed.	Tyrphostins	68-78	tumor necrosis factor	Homo sapiens	134-143	
10734059-6	2000	Tyrphostin, an inhibitor of the EGF receptor intrinsic tryosine kinase, prevented or markedly attenuated the decrease in apoB secretion by TNF-alpha or IL-1beta.	Tyrphostins	0-10	tumor necrosis factor	Homo sapiens	139-148	
9416416-0	1997	Inhibition of transforming growth factor alpha stimulation of human squamous cell carcinoma of the head and neck with anti-TGF-alpha antibodies and tyrphostin.	Tyrphostins	148-158	tumor necrosis factor	Homo sapiens	14-46	
8660850-6	1996	In addition, strong inhibition (81%) of BCG-induced TNF-alpha secretion was observed with tyrphostin (30 microM), another specific protein tyrosine kinase with a different mechanism of action.	Tyrphostins	90-100	tumor necrosis factor	Homo sapiens	52-61	
8061118-5	1994	Incubation of tumor cells with genistein or tyrphostin, known TK inhibitors, protected against TNF cytotoxicity in a dose-dependent manner.	Tyrphostins	44-54	tumor necrosis factor	Homo sapiens	95-98