PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9237626-0 1997 Tyrphostin AG 494 blocks Cdk2 activation. Tyrphostins 0-10 cyclin dependent kinase 2 Homo sapiens 25-29 10454524-9 1999 Previous and present results indicate that group 1 tyrphostins, which inhibit Cdk2 activation, and group 2 tyrphostins, represented by AG1478, a potent epidermal growth factor receptor kinase inhibitor, induce cell cycle arrest; and, in the case of HF-1 cells, apoptosis and differentiation. Tyrphostins 51-62 cyclin dependent kinase 2 Homo sapiens 78-82 9637776-0 1998 Inhibition of Cdk2 activation by selected tyrphostins causes cell cycle arrest at late G1 and S phase. Tyrphostins 42-53 cyclin dependent kinase 2 Homo sapiens 14-18 9637776-11 1998 Further analysis revealed that these tyrphostins act by inhibiting the activation of the enzyme Cdk2 without affecting its levels or its intrinsic kinase activity. Tyrphostins 37-48 cyclin dependent kinase 2 Homo sapiens 96-100 9407975-0 1997 Correspondence re: G. Palumbo et al., the tyrphostin AG17 induces apoptosis and inhibition of cdk2 activity in a lymphoma cell line that overexpresses bcl-2. Tyrphostins 42-52 cyclin dependent kinase 2 Homo sapiens 94-98