PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15355899-8 2004 Blockade of the EGFR with the tyrphostin AG1478 eliminates the up-regulation XRCC1 and ERCC1 by TGF alpha or irradiation. Tyrphostins 30-40 transforming growth factor alpha Homo sapiens 96-105 21887406-11 2011 A comparison of the effects of the investigated tyrphostins indicates that TGFalpha, IGFII and VEGF stimulate cell growth by affecting the same signaling pathway. Tyrphostins 48-59 transforming growth factor alpha Homo sapiens 75-83 8083760-7 1994 Blockade of EGFR with either tyrphostin RG-50864, an inhibitor of tyrosine kinase activity, or a monoclonal antibody that prevents ligand binding abolished the upregulatory effect of TGF alpha on TGF alpha mRNA levels. Tyrphostins 29-39 transforming growth factor alpha Homo sapiens 183-192 10508495-6 1999 Inhibition of ErbB-2 kinase activity by tyrphostin AG825 prevented the constitutive activation of STAT 3 in the TGF-alpha-producing, ErbB-1 expressing cell line. Tyrphostins 40-50 transforming growth factor alpha Homo sapiens 112-121 7628051-10 1995 Tyrphostins B46 and B56 inhibited DNA synthesis stimulated by TGF alpha in defined medium to a greater extent than DNA synthesis stimulated by serum. Tyrphostins 0-11 transforming growth factor alpha Homo sapiens 62-71 7628051-13 1995 These results demonstrate that protein binding accounts for the apparent selectivity of some highly protein-bound tyrphostins for TGF alpha-stimulated DNA synthesis of L23/P cells. Tyrphostins 114-125 transforming growth factor alpha Homo sapiens 130-139 10722725-6 2000 The increase of c-Met phosphorylation by TGFalpha in A431 cells was inhibited by neutralizing antibodies against TGFalpha and/or EGFR and by the EGFR-specific inhibitor tyrphostin AG1478. Tyrphostins 169-179 transforming growth factor alpha Homo sapiens 41-49