PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28680364-0	2016	Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans.	Daptomycin	0-10	ribosomal protein S19	Homo sapiens	44-65	
28680364-7	2016	The unbiased interrogation of human cDNA libraries, displayed on bacteriophage T7, revealed a single human target of daptomycin; ribosomal protein S19.	Daptomycin	117-127	ribosomal protein S19	Homo sapiens	129-150	
28680364-8	2016	Using a drug affinity responsive target stability (DARTS) assay in vitro, we show that daptomycin stabilizes RPS19 toward pronase.	Daptomycin	87-97	ribosomal protein S19	Homo sapiens	109-114	
28680364-9	2016	Fluorescently labeled daptomycin stained specific structures in HeLa cells and co-localized with a RPS19 antibody.	Daptomycin	22-32	ribosomal protein S19	Homo sapiens	99-104	
28680364-10	2016	CONCLUSION: This study provides, for the first time, a human protein target of daptomycin and identifies RPS19 as a possible anticancer drug target for the development of new pharmacological applications and research.	Daptomycin	79-89	ribosomal protein S19	Homo sapiens	105-110	
34253886-0	2021	Daptomycin suppresses tumor migration and angiogenesis via binding to ribosomal protein S19 in humans.	Daptomycin	0-10	ribosomal protein S19	Homo sapiens	70-91	
34253886-4	2021	Engagement of RPS19 by DAP was shown by CETSA and ITDRFCETSA assays, and knocking down of RPS19 with siRNA increased the potency of DAP in MCF7 cells.	Daptomycin	132-135	ribosomal protein S19	Homo sapiens	14-19	
34253886-4	2021	Engagement of RPS19 by DAP was shown by CETSA and ITDRFCETSA assays, and knocking down of RPS19 with siRNA increased the potency of DAP in MCF7 cells.	Daptomycin	132-135	ribosomal protein S19	Homo sapiens	90-95	
34253886-6	2021	Collectively, these data provide an outline of the underlying mechanism of how DAP exhibits anti-cancer activity and suggests that RPS19 could be a promising target for the development of new anticancer drugs.	Daptomycin	79-82	ribosomal protein S19	Homo sapiens	131-136	
34253886-4	2021	Engagement of RPS19 by DAP was shown by CETSA and ITDRFCETSA assays, and knocking down of RPS19 with siRNA increased the potency of DAP in MCF7 cells.	Daptomycin	23-26	ribosomal protein S19	Homo sapiens	14-19	
34253886-1	2021	We have previously reported that daptomycin (DAP), a last resort antibiotic, binds to ribosomal protein S19 (RPS19) in humans and exhibits selective anti-cancer activity against MCF7 breast cancer cells.	Daptomycin	33-43	ribosomal protein S19	Homo sapiens	86-107	
34253886-1	2021	We have previously reported that daptomycin (DAP), a last resort antibiotic, binds to ribosomal protein S19 (RPS19) in humans and exhibits selective anti-cancer activity against MCF7 breast cancer cells.	Daptomycin	33-43	ribosomal protein S19	Homo sapiens	109-114	
34253886-1	2021	We have previously reported that daptomycin (DAP), a last resort antibiotic, binds to ribosomal protein S19 (RPS19) in humans and exhibits selective anti-cancer activity against MCF7 breast cancer cells.	Daptomycin	45-48	ribosomal protein S19	Homo sapiens	86-107	
34253886-1	2021	We have previously reported that daptomycin (DAP), a last resort antibiotic, binds to ribosomal protein S19 (RPS19) in humans and exhibits selective anti-cancer activity against MCF7 breast cancer cells.	Daptomycin	45-48	ribosomal protein S19	Homo sapiens	109-114