PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34794579-2	2021	In this study, we describe the development of a reliable and novel fluorescent assay for ALP detection based on chitosan carbon dots (C-CDs, peak emission, 412 nm) and calcein (peak emission, 512 nm).	fluorexon	168-175	alkaline phosphatase, placental	Homo sapiens	89-92	
34794579-4	2021	Utilizing the ALP-triggered generation of phosphate ions (PO43-) from the substrate p-nitrophenyl phosphate (pNPP), the Eu3+ ions bind PO43- (which shows a higher affinity toward Eu3+ than calcein), and the fluorescence of calcein is recovered.	fluorexon	189-196	alkaline phosphatase, placental	Homo sapiens	14-17	
34794579-4	2021	Utilizing the ALP-triggered generation of phosphate ions (PO43-) from the substrate p-nitrophenyl phosphate (pNPP), the Eu3+ ions bind PO43- (which shows a higher affinity toward Eu3+ than calcein), and the fluorescence of calcein is recovered.	fluorexon	223-230	alkaline phosphatase, placental	Homo sapiens	14-17	
29392933-1	2018	A simple and cost-effective fluorescence immunoassay for the sensitive quantitation of disease biomarker alpha-fetoprotein (AFP) has been developed based on the phosphate-triggered fluorescence turn-on detection of alkaline phosphatase (ALP), with the reversible binding between calcein and Ce3+ as a signaling element.	fluorexon	279-286	alkaline phosphatase, placental	Homo sapiens	215-235	
29392933-3	2018	The ALP-catalyzed hydrolysis of p-nitrophenyl phosphate leads to the formation of p-nitrophenol and inorganic orthophosphate, and the newly formed orthophosphate could potently combine with Ce3+ due to the higher affinity, thus, recovering the fluorescence of calcein.	fluorexon	260-267	alkaline phosphatase, placental	Homo sapiens	4-7