PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15821150-5	2005	At low concentrations (<0.1 microM), 15d-PGJ(2) inhibited IL-1beta-stimulated prostaglandin E(2) (PGE(2)) but not cytokine (IL-6/IL-8) production or cyclooxygenase-2 (COX-2) expression.	15d-pgj	40-47	C-X-C motif chemokine ligand 8	Homo sapiens	132-136	
22481026-8	2012	CFTR(inh172) also altered the release of inflammation mediators PGE(2) and IL-8, and this effect was blunted by exogenous 15d-PGJ(2).	15d-pgj	122-129	C-X-C motif chemokine ligand 8	Homo sapiens	75-79	
20174873-6	2011	15d-PGJ(2) decreased TLR2 mRNA, increased IL-8 production, and suppressed NF-kappaB activity.	15d-pgj	0-7	C-X-C motif chemokine ligand 8	Homo sapiens	42-46	
20174873-10	2011	Thus, 15d-PGJ(2) can have both anti- and pro-inflammatory effects, and 15d-PGJ(2)-mediated IL-8 up-regulation is related to the mitogen-activated protein kinase (MAPK) and NF-kappaB signaling pathways.	15d-pgj	71-78	C-X-C motif chemokine ligand 8	Homo sapiens	91-95	
18665800-2	2008	It has been demonstrated that 15d-PGJ(2) potently increases the generation of interleukin-8 (IL-8) in human microvascular endothelial cells (HMEC-1s); however, the mechanism of this induction is not known.	15d-pgj	30-37	C-X-C motif chemokine ligand 8	Homo sapiens	78-91	
18665800-2	2008	It has been demonstrated that 15d-PGJ(2) potently increases the generation of interleukin-8 (IL-8) in human microvascular endothelial cells (HMEC-1s); however, the mechanism of this induction is not known.	15d-pgj	30-37	C-X-C motif chemokine ligand 8	Homo sapiens	93-97	
12364456-7	2002	Treatment of placental, amnion, and choriodecidual tissues with both 15d-PGJ(2) and troglitazone significantly reduced the release of lipopolysaccharide-stimulated IL-6, IL-8, and TNF-alpha (t test, P < 0.05).	15d-pgj	69-76	C-X-C motif chemokine ligand 8	Homo sapiens	170-174