PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20118567-5 2010 The production of IL-1alpha and -1beta stimulated with lipopolysaccharide was significantly increased in the presence of amlodipine. Amlodipine 121-131 interleukin 1 alpha Homo sapiens 18-38 20118567-7 2010 Amlodipine and diltiazem significantly increased production of IL-1alpha stimulated with concanavalin A. Amlodipine 0-10 interleukin 1 alpha Homo sapiens 63-72 32141013-11 2020 Gene expression level of TNF-alpha, IL-6 and IL-1beta was significantly reduced by amlodipine while an increase in expression level of IL-4 and IL-10 was evident in animals treated with piroxicam and amlodipine. Amlodipine 83-93 interleukin 1 alpha Homo sapiens 45-53 10704258-9 2000 The production of IL-1alpha, and IL-6 was inhibited by amlodipine in a concentration-dependent manner and was significantly decreased at a concentration of 10 micromol/l. Amlodipine 55-65 interleukin 1 alpha Homo sapiens 18-27 10704258-12 2000 The unique property of amlodipine to inhibit the production of IL-1alpha, IL-1beta and IL-6 may contribute to its beneficial effects in heart failure patients. Amlodipine 23-33 interleukin 1 alpha Homo sapiens 63-72 32141013-12 2020 Molecular docking analysis demonstrated strong binding interaction of amlodipine with TNF-alpha, IL-6 and IL-1beta thus providing a good correlation between experimental and theoretical results. Amlodipine 70-80 interleukin 1 alpha Homo sapiens 106-114