PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25044076-6 2014 Moreover, the levels of brain-derived neurotrophic growth factor (BDNF) and nerve growth factor (NGF) were enhanced in the brains of APP and PS1 mice by the chronic LTG treatment. Lamotrigine 165-168 brain derived neurotrophic factor Mus musculus 24-64 25044076-6 2014 Moreover, the levels of brain-derived neurotrophic growth factor (BDNF) and nerve growth factor (NGF) were enhanced in the brains of APP and PS1 mice by the chronic LTG treatment. Lamotrigine 165-168 brain derived neurotrophic factor Mus musculus 66-70 25044076-7 2014 Therefore, these observations demonstrate that LTG attenuates AD pathology through multiple mechanisms, including modulation of abnormal network activity, reduction of the generation of amyloid beta and upregulation of BDNF and NGF. Lamotrigine 47-50 brain derived neurotrophic factor Mus musculus 219-223