PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24283699-9	2014	Lamotrigine binding to NaV 1.1 subunits is faster than to the other alpha-subunits.	Lamotrigine	0-11	sodium voltage-gated channel alpha subunit 1	Homo sapiens	23-30	
21453355-5	2011	We examined tonic inhibition and use-dependent inhibition of Na(V) 1.1 splice isoforms by phenytoin, carbamazepine, and lamotrigine.	Lamotrigine	120-131	sodium voltage-gated channel alpha subunit 1	Homo sapiens	61-70	
21453355-8	2011	However, Na(V) 1.1-5N channels exhibited enhanced tonic block by phenytoin and lamotrigine compared to Na(V) 1.1-5A.	Lamotrigine	79-90	sodium voltage-gated channel alpha subunit 1	Homo sapiens	9-18	
21453355-9	2011	In addition, Na(V) 1.1-5N exhibited enhanced use-dependent block by phenytoin and lamotrigine across a range of stimulation frequencies and concentrations.	Lamotrigine	82-93	sodium voltage-gated channel alpha subunit 1	Homo sapiens	13-22	
21453355-12	2011	SIGNIFICANCE: These results suggest Na(V) 1.1 channels containing exon 5N are more sensitive to the commonly used antiepileptic drugs phenytoin and lamotrigine.	Lamotrigine	148-159	sodium voltage-gated channel alpha subunit 1	Homo sapiens	36-45	
20037572-0	2009	[Association study of the SCN1 gene polymorphism and effective dose of lamotrigine].	Lamotrigine	71-82	sodium voltage-gated channel alpha subunit 1	Homo sapiens	26-30	
20037572-1	2009	An association between a polymorphism of the SCN1 gene, a therapeutical target of lamotrigine, and an effective dose (a blood plasma concentration) of the drug in patients with epilepsy has been studied.	Lamotrigine	82-93	sodium voltage-gated channel alpha subunit 1	Homo sapiens	45-49	
20037572-6	2009	The hypothesis on the association between the SCN1 IVS5N+5 G>A polymorphism and the effective dose (concentration) of lamotrigine was confirmed.	Lamotrigine	121-132	sodium voltage-gated channel alpha subunit 1	Homo sapiens	46-50