PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35303539-14 2022 Furthermore, our results indicate that it is possible that different UGT genotypes may exert larger impact on LTG metabolism in women than in men. Lamotrigine 110-113 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 69-72 23360413-6 2013 The most pronounced decline in serum concentrations is seen for AEDs that are eliminated by glucuronidation (UGT), in particular lamotrigine where the effect may be profound. Lamotrigine 129-140 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 109-112 21601426-1 2011 Lamotrigine (LTG) which has a widespread use in epilepsy treatment as an antiepileptic agent is metabolized by UDP-glucuronosyl transferase (UGT) enzymes. Lamotrigine 0-11 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 111-139 21601426-1 2011 Lamotrigine (LTG) which has a widespread use in epilepsy treatment as an antiepileptic agent is metabolized by UDP-glucuronosyl transferase (UGT) enzymes. Lamotrigine 0-11 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 141-144 21601426-1 2011 Lamotrigine (LTG) which has a widespread use in epilepsy treatment as an antiepileptic agent is metabolized by UDP-glucuronosyl transferase (UGT) enzymes. Lamotrigine 13-16 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 111-139 21601426-1 2011 Lamotrigine (LTG) which has a widespread use in epilepsy treatment as an antiepileptic agent is metabolized by UDP-glucuronosyl transferase (UGT) enzymes. Lamotrigine 13-16 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 141-144 20713656-6 2010 A correlation analysis of UGT enzymatic activity and the formation rate of glucuronide metabolites from 1"- and 4-hydroxymidazolam in 25 HLMs showed that hydroxymidazolam glucuronidation is correlated with UGT1A4-mediated lamotrigine glucuronidation and UGT2B7-mediated diclofenac glucuronidation activity. Lamotrigine 222-233 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 26-29 9606477-8 1998 Lamotrigine is a weak inducer of UGT. Lamotrigine 0-11 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 33-36 30168665-0 2019 Meta-analysis of the Influence of UGT Genetic Polymorphisms on Lamotrigine Concentration. Lamotrigine 63-74 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 34-37