PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9368570-0	1997	Lamotrigine protects hippocampal CA1 neurons from ischemic damage after cardiac arrest.	Lamotrigine	0-11	carbonic anhydrase 1	Homo sapiens	33-36	
19500574-9	2009	Lamotrigine, known to increase Ih, reversed the impact of KA on burst duration in CA1 at both time-points linking a transcriptional reduction in HCN2 function to increased burst duration.	Lamotrigine	0-11	carbonic anhydrase 1	Homo sapiens	82-85	
18559277-9	2008	Finally, when lamotrigine, an enhancer of dendritic I(h), was applied immediately after ischemia, there was a significant attenuation of CA1 cell loss.	Lamotrigine	14-25	carbonic anhydrase 1	Homo sapiens	137-140	
7886726-8	1995	Lamotrigine significantly prevented loss of hippocampal CA1 neurons when administered acutely (100 mg/kg PO) immediately after reperfusion or when administered in two equal doses of 30 or 50 mg/kg 2 hours before and immediately after reperfusion.	Lamotrigine	0-11	carbonic anhydrase 1	Homo sapiens	56-59	
7886726-13	1995	Lamotrigine completely protected gerbils exposed to 15 minutes of cerebral ischemia against CA3 cell loss and greatly reduced damage to the CA1 and CA2 cell tracts of the hippocampus.	Lamotrigine	0-11	carbonic anhydrase 1	Homo sapiens	140-143	
7537844-4	1995	Slice perfusion with 1.2-1.6 mM felbamate or 100 microM lamotrigine significantly decreased the incidence of the irreversible disappearance of the CA1 electrical response induced by kainic acid.	Lamotrigine	56-67	carbonic anhydrase 1	Homo sapiens	147-150