PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11373274-4	2001	We found that staurosporine, a broad-specificity kinase inhibitor and inducer of cell apoptosis, attenuated PKB activation exclusively through the inhibition of Thr-308 phosphorylation, with Ser-473 phosphorylation unaffected.	Staurosporine	14-27	protein tyrosine kinase 2 beta	Homo sapiens	108-111	
19880522-13	2010	Staurosporine stress of ID8 cells promoted endogenous Pyk2 nuclear accumulation and enhanced Pyk2 binding to p53.	Staurosporine	0-13	protein tyrosine kinase 2 beta	Homo sapiens	54-58	
19880522-13	2010	Staurosporine stress of ID8 cells promoted endogenous Pyk2 nuclear accumulation and enhanced Pyk2 binding to p53.	Staurosporine	0-13	protein tyrosine kinase 2 beta	Homo sapiens	93-97	
19880522-14	2010	Pyk2 knockdown potentiated ID8 cell death upon staurosporine addition.	Staurosporine	47-60	protein tyrosine kinase 2 beta	Homo sapiens	0-4	
18716132-5	2008	Pretreatment of these cells with the PTK inhibitor staurosporine led to sustained STAT6 phosphorylation consistent with STAT6 serving as a direct substrate of PTP1B.	Staurosporine	51-64	protein tyrosine kinase 2 beta	Homo sapiens	37-40	
11373274-8	2001	Moreover, our results suggest that inhibition of PKB signaling is involved in the proapoptotic action of staurosporine.	Staurosporine	105-118	protein tyrosine kinase 2 beta	Homo sapiens	49-52	
8996546-4	1996	In both parental drug sensitive HL-60 cells and Pgp/p170 positive (MDR1) HL-60/VCR, staurosporine-stimulated AraC-induced apoptosis was higher than that stimulated by the PKC selective CGP 41251 inhibitor, or PTK-inhibitor genistein.	Staurosporine	84-97	protein tyrosine kinase 2 beta	Homo sapiens	209-212	
10093970-3	1999	While PYK2 tyrosine phosphorylation induced by thrombin was inhibited by preincubation of platelets with PKC inhibitors, staurosporine and Ro31-8220, PYK2 association with Src was markedly enhanced under the same conditions.	Staurosporine	121-134	protein tyrosine kinase 2 beta	Homo sapiens	6-10	
1879563-3	1991	We have shown in a rat fibroblast line that staurosporine is a potent PTK inhibitor capable of clearly discriminating the two types of receptor-stimulated Ca2+ mobilization and, by inference, PLC activations the response triggered by PDGF was completely inhibited, whereas the responses triggered by vasopressin, bombesin and PGF2 alpha were not affected at all.	Staurosporine	44-57	protein tyrosine kinase 2 beta	Homo sapiens	70-73