PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31085166-10 2019 Moreover, treatments with DRP1 inhibitor, mdivi-1, or with DRP1-targetted siRNA efficiently prevent silibinin-induced apoptosis in the breast cancer cells, whereas inhibition of DRP1 phosphorylation with staurosporine increases apoptosis furthermore. Staurosporine 204-217 dynamin 1 like Homo sapiens 59-63 15469822-5 2004 Conversely, the sensitivity to staurosporine-induced apoptosis, previously shown to be directly triggered by Drp-1-dependent recruitment of proapoptotic proteins to mitochondria, was enhanced. Staurosporine 31-44 dynamin 1 like Homo sapiens 109-114 35158046-8 2022 Accordingly, inhibition of DRP1 activity with its pharmacological inhibitor or siDRP1 efficiently attenuated ethanol- or acetaldehyde-induced apoptosis, whereas activation of DRP1 by using staurosporine (STS) further increased apoptosis in ethanol- or acetaldehyde-treated HepG2 or HL7702 cells. Staurosporine 189-202 dynamin 1 like Homo sapiens 27-31 35158046-8 2022 Accordingly, inhibition of DRP1 activity with its pharmacological inhibitor or siDRP1 efficiently attenuated ethanol- or acetaldehyde-induced apoptosis, whereas activation of DRP1 by using staurosporine (STS) further increased apoptosis in ethanol- or acetaldehyde-treated HepG2 or HL7702 cells. Staurosporine 189-202 dynamin 1 like Homo sapiens 175-179 31085166-10 2019 Moreover, treatments with DRP1 inhibitor, mdivi-1, or with DRP1-targetted siRNA efficiently prevent silibinin-induced apoptosis in the breast cancer cells, whereas inhibition of DRP1 phosphorylation with staurosporine increases apoptosis furthermore. Staurosporine 204-217 dynamin 1 like Homo sapiens 59-63 23798729-6 2013 Drp1-x01 stabilized and bundled microtubules and attenuated staurosporine-induced mitochondrial fragmentation and apoptosis. Staurosporine 60-73 dynamin 1 like Homo sapiens 0-4 19638400-6 2009 Although initial analysis indicates that mitochondrial recruitment of ectopically expressed Drp1 in response to staurosporine is unaffected by loss of SUMOylation, we find that Drp1 SUMOylation is enhanced in the context of the K38A mutation. Staurosporine 112-125 dynamin 1 like Homo sapiens 92-96