PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10673221-5 2000 The Arg-51 in LTC4 synthase has been suggested to function as proton donor for the opening of the LTA4 epoxide. Epoxy Compounds 103-110 leukotriene C4 synthase Homo sapiens 14-27 12895593-6 2003 Site-directed mutagenesis of LTC(4) synthase suggests that Arg-51 is involved in opening the epoxide ring of LTA(4) and Tyr-93 in GSH thiolate anion formation during catalytic conjugation. Epoxy Compounds 93-100 leukotriene C4 synthase Homo sapiens 29-44 9153254-9 1997 These results suggest that in the catalytic function of LTC4S, Arg-51 probably opens the epoxide ring and Tyr-93 provides the thiolate anion of GSH. Epoxy Compounds 89-96 leukotriene C4 synthase Homo sapiens 56-61