PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23500058-0	2013	Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system.	Cyclodextrins	80-92	tumor necrosis factor	Mus musculus	18-27	
17079792-8	2007	Modification of lipid rafts by cyclodextrin and nystatin corrected the abnormal response, suggesting an association between the increased lipid rafts and abnormal TNF-alpha secretion.	Cyclodextrins	31-43	tumor necrosis factor	Mus musculus	163-172	
27482889-5	2016	TNF-induced albuminuria was aggravated in mice with podocyte-specific ABCA1 deficiency and was partially prevented by cholesterol depletion with cyclodextrin.	Cyclodextrins	145-157	tumor necrosis factor	Mus musculus	0-3	
23500058-11	2013	This data indicates the clinical potential of a local CD-based TNF-alpha siRNA delivery system for the treatment of IBD.	Cyclodextrins	54-56	tumor necrosis factor	Mus musculus	63-72	
23500058-4	2013	The aim of this study was to investigate the efficacy of an amphiphilic cationic cyclodextrin (CD) vector for effective TNF-alpha siRNA delivery to macrophage cells and to mice with induced acute-colitis.	Cyclodextrins	81-93	tumor necrosis factor	Mus musculus	120-129	
23500058-4	2013	The aim of this study was to investigate the efficacy of an amphiphilic cationic cyclodextrin (CD) vector for effective TNF-alpha siRNA delivery to macrophage cells and to mice with induced acute-colitis.	Cyclodextrins	95-97	tumor necrosis factor	Mus musculus	120-129	
23500058-6	2013	RAW264.7 cells were transfected with CD.TNF-alpha siRNA, stimulated with lipopolysaccharide (LPS) and TNF-alpha and IL-6 responses were measured by PCR and ELISA.	Cyclodextrins	37-39	tumor necrosis factor	Mus musculus	40-49	
23500058-9	2013	RAW264.7 cells transfected with CD.TNF-alpha siRNA and stimulated with LPS displayed a significant reduction in both gene and protein levels of TNF-alpha and IL-6.	Cyclodextrins	32-34	tumor necrosis factor	Mus musculus	35-44	
23500058-9	2013	RAW264.7 cells transfected with CD.TNF-alpha siRNA and stimulated with LPS displayed a significant reduction in both gene and protein levels of TNF-alpha and IL-6.	Cyclodextrins	32-34	tumor necrosis factor	Mus musculus	144-153	
23500058-10	2013	CD.TNF-alpha siRNA-treated mice revealed a mild amelioration in clinical signs of colitis, but significant reductions in total colon weight and colonic mRNA expression of TNF-alpha and IL-6 compared to DSS-control mice were detected.	Cyclodextrins	0-2	tumor necrosis factor	Mus musculus	3-12