PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9629899-5	1998	The patterns of apoB-Lp in IEF with the CDs appeared to differ in some sera.	Cyclodextrins	40-43	apolipoprotein B	Homo sapiens	16-20	
9270972-4	1997	Prolonged daily (4 d or more) administration of 0.5% (3.5 mM) cyclodextrin with medium containing 10% fetal bovine serum increased the secretion of nascent apoB from 5-10% (control) to 17-28% and cellular undegraded apoB from 15-20% (control) to 25-31% of apoB synthesized, respectively.	Cyclodextrins	62-74	apolipoprotein B	Homo sapiens	216-220	
9270972-5	1997	Subsequent administration of cyclodextrin solubilized cholesterol (10-40 micrograms) for only 3 h reversed the cyclodextrin-mediated increase in apoB secretion.	Cyclodextrins	29-41	apolipoprotein B	Homo sapiens	145-149	
9270972-5	1997	Subsequent administration of cyclodextrin solubilized cholesterol (10-40 micrograms) for only 3 h reversed the cyclodextrin-mediated increase in apoB secretion.	Cyclodextrins	111-123	apolipoprotein B	Homo sapiens	145-149	
9270972-8	1997	However, prolonged (15 d) administration of cyclodextrin was shown to increase the cellular free cholesterol concentration by 25-41%, reduce the cellular triglyceride concentration by 59%, and increase apoB secretion 3- to 4-fold, without affecting the cellular cholesteryl ester concentration.	Cyclodextrins	44-56	apolipoprotein B	Homo sapiens	202-206	
9270972-9	1997	In comparison, 14-d treatment with cyclodextrin-solubilized cholesterol (20 micrograms/mL) followed by 1-d equilibration without cholesterol was shown to increase the cellular free cholesterol and cholesteryl ester concentrations by 76% and 10-fold, respectively, although apoB secretion was not affected.	Cyclodextrins	35-47	apolipoprotein B	Homo sapiens	273-277	
9270972-10	1997	It is hypothesized that chronic daily administration of 0.5% cyclodextrin increased the cellular cholesterol concentration and flux in discrete putative regulatory compartments, which "shielded" nascent apoB from rapid proteolysis and facilitated apoB secretion.	Cyclodextrins	61-73	apolipoprotein B	Homo sapiens	203-207	
9270972-10	1997	It is hypothesized that chronic daily administration of 0.5% cyclodextrin increased the cellular cholesterol concentration and flux in discrete putative regulatory compartments, which "shielded" nascent apoB from rapid proteolysis and facilitated apoB secretion.	Cyclodextrins	61-73	apolipoprotein B	Homo sapiens	247-251	
9270972-11	1997	In conclusion, cyclodextrin was used independently and in combination with cholesterol or oleate to modulate apoB proteolysis and secretion.	Cyclodextrins	15-27	apolipoprotein B	Homo sapiens	109-113	
9270972-0	1997	Use of cyclodextrin to deliver lipids and to modulate apolipoprotein B-100 production in HepG2 cells.	Cyclodextrins	7-19	apolipoprotein B	Homo sapiens	54-74	
9270972-3	1997	Three-hour treatment with cyclodextrin-solubilized oleate (0.2 mM) increased secreted apoB from 4% (control cells) to 32% and cellular undegraded apoB from 15% (control cells to 64% of apoB synthesized, which is consistent with earlier studies using bovine serum albumin to complex exogenous oleate.	Cyclodextrins	26-38	apolipoprotein B	Homo sapiens	86-90	
9270972-3	1997	Three-hour treatment with cyclodextrin-solubilized oleate (0.2 mM) increased secreted apoB from 4% (control cells) to 32% and cellular undegraded apoB from 15% (control cells to 64% of apoB synthesized, which is consistent with earlier studies using bovine serum albumin to complex exogenous oleate.	Cyclodextrins	26-38	apolipoprotein B	Homo sapiens	146-150	
9270972-3	1997	Three-hour treatment with cyclodextrin-solubilized oleate (0.2 mM) increased secreted apoB from 4% (control cells) to 32% and cellular undegraded apoB from 15% (control cells to 64% of apoB synthesized, which is consistent with earlier studies using bovine serum albumin to complex exogenous oleate.	Cyclodextrins	26-38	apolipoprotein B	Homo sapiens	146-150	
9270972-4	1997	Prolonged daily (4 d or more) administration of 0.5% (3.5 mM) cyclodextrin with medium containing 10% fetal bovine serum increased the secretion of nascent apoB from 5-10% (control) to 17-28% and cellular undegraded apoB from 15-20% (control) to 25-31% of apoB synthesized, respectively.	Cyclodextrins	62-74	apolipoprotein B	Homo sapiens	156-160	
9270972-4	1997	Prolonged daily (4 d or more) administration of 0.5% (3.5 mM) cyclodextrin with medium containing 10% fetal bovine serum increased the secretion of nascent apoB from 5-10% (control) to 17-28% and cellular undegraded apoB from 15-20% (control) to 25-31% of apoB synthesized, respectively.	Cyclodextrins	62-74	apolipoprotein B	Homo sapiens	216-220