PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32579062-3 2021 Using a combination of molecular modeling and simulation techniques, in this study the effects of five carbohydrate polymers of Chitosan, Alginate, Cyclodextrin, Hyaluronic acid and Pectin on structure and dynamics of interleukin2 protein at 298 K and 343 K, are investigated. Cyclodextrins 148-160 interleukin 2 Homo sapiens 218-230 32579062-5 2021 Among different polymers, Chitosan and Cyclodextrin have shown to be able to protect protein against the negative effects of high temperatures in comparison with other polymers which suggests that the use of Cyclodextrin biopolymer for the preparation of pharmaceutical formulations of interleukin2 can be the best possible choice among other polymers investigated in this research.Communicated by Ramaswamy H. Sarma. Cyclodextrins 39-51 interleukin 2 Homo sapiens 286-298 32579062-5 2021 Among different polymers, Chitosan and Cyclodextrin have shown to be able to protect protein against the negative effects of high temperatures in comparison with other polymers which suggests that the use of Cyclodextrin biopolymer for the preparation of pharmaceutical formulations of interleukin2 can be the best possible choice among other polymers investigated in this research.Communicated by Ramaswamy H. Sarma. Cyclodextrins 208-220 interleukin 2 Homo sapiens 286-298 22084730-4 2011 This combination of cyclodextrin + interleukin-2 led to the decrease of interleukin-2 effective concentration by an order. Cyclodextrins 20-32 interleukin 2 Homo sapiens 72-85