PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7747284-10	1995	Because of the decreasing ratio in activity between CYP2E1 and CYP3A4 with respect to the oxidation of chlorinated benzenes, it is concluded that the role of CYP2E1 toward chlorinated benzenes decreases with increasing number of chlorine atoms.	Chlorine	229-237	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	52-58	
30025364-7	2018	This study suggests that tri- and tetrachlorobiphenyls with a single ortho chlorine can be most mutagenic under activation by human CYP2E1, and greater numbers of ortho chlorines may cause a drastic decline in the activity, especially for tetrachlorobiphenyls.	Chlorine	75-83	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	132-138	
30025364-2	2018	We have reported the mutagenicity of some PCBs with one to four chlorines in mammalian cells expressing human CYP2E1.	Chlorine	64-73	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	110-116	
15997102-4	2005	The effects of halogen-substitution in 32 aniline derivatives on the CYP2E1 inhibition can be summarized as follows: more enhancement by chlorine- and bromine-substitution than by fluorine-substitution, more enhancement by para- and metha-halogen-substitution than by ortho-halogen-substitution, and more enhancement by dihalogen-substitution than by mono- and trihalogen-substitution except for trifluorine-substitution.	Chlorine	137-145	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	69-75	
7747284-10	1995	Because of the decreasing ratio in activity between CYP2E1 and CYP3A4 with respect to the oxidation of chlorinated benzenes, it is concluded that the role of CYP2E1 toward chlorinated benzenes decreases with increasing number of chlorine atoms.	Chlorine	229-237	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	158-164