PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15782327-0 2005 Metal components analysis of metallothionein-III in the brain sections of metallothionein-I and metallothionein-II null mice exposed to mercury vapor with HPLC/ICP-MS. Mercury vapor is effectively absorbed via inhalation and easily passes through the blood-brain barrier; therefore, mercury poisoning with primarily central nervous system symptoms occurs. Mercury 168-175 metallothionein 1 Mus musculus 29-46 27802831-2 2016 Previously, we found in mice that knockout of MT 1 and 2 genes (MTKO) impaired spatial learning and potentiated the learning impairment caused by developmental mercury exposure. Mercury 160-167 metallothionein 1 Mus musculus 46-56 22008530-0 2011 Neurobehavioral changes and alteration of gene expression in the brains of metallothionein-I/II null mice exposed to low levels of mercury vapor during postnatal development. Mercury 131-138 metallothionein 1 Mus musculus 75-92 21518240-4 2011 We report here the development of a transplastomic approach to express the mouse metallothionein gene (mt1) and accumulate mercury in high concentrations within plant cells. Mercury 123-130 metallothionein 1 Mus musculus 103-106 18226494-0 2008 Mercury-induced cognitive impairment in metallothionein-1/2 null mice. Mercury 0-7 metallothionein 1 Mus musculus 40-57 15782327-10 2005 The mercury accumulated in brains after mercury vapor exposure for MT-I, II null mice and wild-type mice. Mercury 4-11 metallothionein 1 Mus musculus 67-71 15782327-11 2005 The mercury levels of MT-I, II null mice in each brain section were significantly higher than those of wild-type mice after mercury vapor exposure. Mercury 4-11 metallothionein 1 Mus musculus 22-26 15782327-11 2005 The mercury levels of MT-I, II null mice in each brain section were significantly higher than those of wild-type mice after mercury vapor exposure. Mercury 124-131 metallothionein 1 Mus musculus 22-26 15782327-12 2005 A significant change of zinc concentrations with the following mercury vapor exposure for MT-I, II null mice was observed only in the cerebellum analyzed by two-way analysis of variance. Mercury 63-70 metallothionein 1 Mus musculus 90-94 15782327-14 2005 Metal components of metal-binding proteins of soluble fractions in the brain sections were analyzed by size-exclusion high-performance liquid chromatography (HPLC) connected with ICP-MS. From the results of HPLC/ICP-MS analyses, it was concluded that the mercury components of MT-III and high molecular weight metal-binding proteins in the cerebellum of MT-I, II null mice were much higher than those of wild-type mice. Mercury 255-262 metallothionein 1 Mus musculus 277-281 15782327-15 2005 It was suggested that MT-III is associated with the storage of mercury in conditions lacking MT-I, and MT-II. Mercury 63-70 metallothionein 1 Mus musculus 22-26 15782327-16 2005 It was also suggested that the physiological role of MT-III and some kind of high molecular weight proteins might be impaired by exposure to mercury vapor and lack of MT-I and MT-II. Mercury 141-148 metallothionein 1 Mus musculus 53-57 15603537-8 2004 MT-I & -II immunoreactivity, which was confined to wild-type mice, was demonstrated in the yolk sac and decidual cells; mercury was also shown in both structures, suggesting that mercury granules were bound to MTs. Mercury 183-190 metallothionein 1 Mus musculus 0-4 29618716-10 2018 The present study found that GSH and MT-I/II play cooperatively an important role in the detoxification of severe kidney damage caused by inorganic mercury. Mercury 148-155 metallothionein 1 Mus musculus 37-41