PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17382299-3	2007	At nanomolar concentrations, CLOM and DMI increased expression of phospho-CREB (cyclic AMP response element binding protein).	Desipramine	38-41	cAMP responsive element binding protein 1	Homo sapiens	74-78	
19424057-3	2009	Here, we investigated whether chronic restraint stress (14 days) and antidepressant treatment [desipramine (DMI), 10 mg/kg intraperitoneally] induce changes in animal behavior and hippocampal levels of phospho-ERK1/2 and its substrate phospho-cAMP response element-binding protein (CREB).	Desipramine	95-106	cAMP responsive element binding protein 1	Homo sapiens	282-286	
15138445-4	2004	We investigated how different drugs (fluoxetine (FLX), desipramine (DMI), reboxetine (RBX)) affect CREB expression and phosphorylation of Ser(133) in the hippocampus and prefrontal/frontal cortex (PFCX).	Desipramine	55-66	cAMP responsive element binding protein 1	Homo sapiens	99-103	
16036225-4	2005	This effect of DMI was not dependent upon activity at the levels of the beta2 receptor, cAMP accumulation or phosphorylation of the transcription factor, cAMP response element binding protein (CREB).	Desipramine	15-18	cAMP responsive element binding protein 1	Homo sapiens	193-197	
16036225-8	2005	The results suggest a molecular target for DMI that lies downstream of CREB phosphorylation.	Desipramine	43-46	cAMP responsive element binding protein 1	Homo sapiens	71-75	
15138445-4	2004	We investigated how different drugs (fluoxetine (FLX), desipramine (DMI), reboxetine (RBX)) affect CREB expression and phosphorylation of Ser(133) in the hippocampus and prefrontal/frontal cortex (PFCX).	Desipramine	68-71	cAMP responsive element binding protein 1	Homo sapiens	99-103