PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28258219-1	2017	Pyrroline-5-carboxylate reductase (PYCR) is the final enzyme in proline biosynthesis, catalyzing the NAD(P)H-dependent reduction of Delta1-pyrroline-5-carboxylate (P5C) to proline.	nad(p)h	101-108	pyrroline-5-carboxylate reductase 1	Homo sapiens	0-33	
33771508-1	2021	Pyrroline-5-carboxylate reductase (PYCR in humans) catalyzes the final step of l-proline biosynthesis by catalyzing the reduction of L-Delta1-pyrroline-5-carboxylate (L-P5C) to l-proline using NAD(P)H as the hydride donor.	nad(p)h	193-200	pyrroline-5-carboxylate reductase 1	Homo sapiens	35-39	
33109600-1	2020	Pyrroline-5-carboxylate reductase 1 (PYCR1) catalyzes the biosynthetic half-reaction of the proline cycle by reducing Delta1-pyrroline-5-carboxylate (P5C) to proline through the oxidation of NAD(P)H.	nad(p)h	191-198	pyrroline-5-carboxylate reductase 1	Homo sapiens	0-35	
33109600-1	2020	Pyrroline-5-carboxylate reductase 1 (PYCR1) catalyzes the biosynthetic half-reaction of the proline cycle by reducing Delta1-pyrroline-5-carboxylate (P5C) to proline through the oxidation of NAD(P)H.	nad(p)h	191-198	pyrroline-5-carboxylate reductase 1	Homo sapiens	37-42	
33109600-1	2020	Pyrroline-5-carboxylate reductase 1 (PYCR1) catalyzes the biosynthetic half-reaction of the proline cycle by reducing Delta1-pyrroline-5-carboxylate (P5C) to proline through the oxidation of NAD(P)H.	nad(p)h	191-198	pyrroline-5-carboxylate reductase 1	Homo sapiens	124-148	
27677826-1	2017	Pyrroline-5-carboxylate reductase (P5CR) encoded by PYCR1 gene is a housekeeping enzyme that catalyzes the reduction of P5C to proline using NAD(P)H as the cofactor.	nad(p)h	141-148	pyrroline-5-carboxylate reductase 1	Homo sapiens	0-33	
27677826-1	2017	Pyrroline-5-carboxylate reductase (P5CR) encoded by PYCR1 gene is a housekeeping enzyme that catalyzes the reduction of P5C to proline using NAD(P)H as the cofactor.	nad(p)h	141-148	pyrroline-5-carboxylate reductase 1	Homo sapiens	35-39	
27677826-1	2017	Pyrroline-5-carboxylate reductase (P5CR) encoded by PYCR1 gene is a housekeeping enzyme that catalyzes the reduction of P5C to proline using NAD(P)H as the cofactor.	nad(p)h	141-148	pyrroline-5-carboxylate reductase 1	Homo sapiens	52-57	
27677826-1	2017	Pyrroline-5-carboxylate reductase (P5CR) encoded by PYCR1 gene is a housekeeping enzyme that catalyzes the reduction of P5C to proline using NAD(P)H as the cofactor.	nad(p)h	141-148	pyrroline-5-carboxylate reductase 1	Homo sapiens	35-38	
28258219-1	2017	Pyrroline-5-carboxylate reductase (PYCR) is the final enzyme in proline biosynthesis, catalyzing the NAD(P)H-dependent reduction of Delta1-pyrroline-5-carboxylate (P5C) to proline.	nad(p)h	101-108	pyrroline-5-carboxylate reductase 1	Homo sapiens	35-39	
28258219-1	2017	Pyrroline-5-carboxylate reductase (PYCR) is the final enzyme in proline biosynthesis, catalyzing the NAD(P)H-dependent reduction of Delta1-pyrroline-5-carboxylate (P5C) to proline.	nad(p)h	101-108	pyrroline-5-carboxylate reductase 1	Homo sapiens	138-162	
28258219-1	2017	Pyrroline-5-carboxylate reductase (PYCR) is the final enzyme in proline biosynthesis, catalyzing the NAD(P)H-dependent reduction of Delta1-pyrroline-5-carboxylate (P5C) to proline.	nad(p)h	101-108	pyrroline-5-carboxylate reductase 1	Homo sapiens	164-167	
18401542-1	2008	Mammalian Delta(1)-pyrroline-5-carboxylate synthase (P5CS) is a bifunctional ATP- and NAD(P)H-dependent mitochondrial enzyme that catalyzes the coupled phosphorylation and reduction-conversion of L: -glutamate to P5C, a pivotal step in the biosynthesis of L: -proline, L: -ornithine and L: -arginine.	nad(p)h	86-93	pyrroline-5-carboxylate reductase 1	Homo sapiens	53-56	
16233902-3	2005	In both pathways, the last step of biosynthesis, the conversion of delta1-pyrroline-5-carboxylate (P5C) to L-proline, is catalyzed by delta1-pyrroline-5-carboxylate reductase (P5CR) using NAD(P)H as a cofactor.	nad(p)h	188-195	pyrroline-5-carboxylate reductase 1	Homo sapiens	67-97	
16233902-3	2005	In both pathways, the last step of biosynthesis, the conversion of delta1-pyrroline-5-carboxylate (P5C) to L-proline, is catalyzed by delta1-pyrroline-5-carboxylate reductase (P5CR) using NAD(P)H as a cofactor.	nad(p)h	188-195	pyrroline-5-carboxylate reductase 1	Homo sapiens	99-102	
16730026-1	2006	Pyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that catalyzes the reduction of Delta(1)-pyrroline-5-carboxylate (P5C) to proline using NAD(P)H as the cofactor.	nad(p)h	164-171	pyrroline-5-carboxylate reductase 1	Homo sapiens	0-33	
16730026-1	2006	Pyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that catalyzes the reduction of Delta(1)-pyrroline-5-carboxylate (P5C) to proline using NAD(P)H as the cofactor.	nad(p)h	164-171	pyrroline-5-carboxylate reductase 1	Homo sapiens	35-39	
16730026-1	2006	Pyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that catalyzes the reduction of Delta(1)-pyrroline-5-carboxylate (P5C) to proline using NAD(P)H as the cofactor.	nad(p)h	164-171	pyrroline-5-carboxylate reductase 1	Homo sapiens	108-140	
16730026-3	2006	Here, we present the 2.8 Angstroms resolution structure of the P5CR apo enzyme, its 3.1 Angstroms resolution ternary complex with NAD(P)H and substrate-analog.	nad(p)h	130-137	pyrroline-5-carboxylate reductase 1	Homo sapiens	63-67	
16233902-3	2005	In both pathways, the last step of biosynthesis, the conversion of delta1-pyrroline-5-carboxylate (P5C) to L-proline, is catalyzed by delta1-pyrroline-5-carboxylate reductase (P5CR) using NAD(P)H as a cofactor.	nad(p)h	188-195	pyrroline-5-carboxylate reductase 1	Homo sapiens	134-174