PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28392690-7 2017 In the in vitro cytotoxic test, HA-nimesulide conjugate displayed >46% cell killing ability at a nimesulide concentration of 400 microM in HT-29 cells, whereas exiguous cytotoxic effects were observed on HCT-15 cells, indicating that HA-nimesulide causes cell death in CD44-overexpressing HT-29 cells. nimesulide 35-45 CD44 molecule (Indian blood group) Homo sapiens 272-276 28392690-9 2017 These results indicated that HA-nimesulide with improved selectivity through HA/CD44 receptor interactions has the potential to enhance the therapeutic efficacy and safety of nimesulide for cancer treatment. nimesulide 32-42 CD44 molecule (Indian blood group) Homo sapiens 80-84