PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12411468-4 2002 The vasoconstriction elicited by COX-2 inhibition was greater when NO production was inhibited because glomerular filtration rate decreased by >25% when nimesulide was administered to dogs with a reduced NO synthesis. nimesulide 156-166 prostaglandin-endoperoxide synthase 2 Canis lupus familiaris 33-38 11348485-0 2001 Pharmacokinetic profile and in vitro selective cyclooxygenase-2 inhibition by nimesulide in the dog. nimesulide 78-88 prostaglandin-endoperoxide synthase 2 Canis lupus familiaris 47-63