PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11518028-5 2001 Imperatorin and isoimperatorin exhibited strong-to-medium inhibition on cyclooxygenase-1- and cyclooxygenase-2-catalysed prostaglandin E2 release, with inhibition percentages similar to those of the reference drugs, indometacin and nimesulide, respectively. nimesulide 232-242 prostaglandin-endoperoxide synthase 1 Mus musculus 72-88 17166728-5 2007 Pups pretreated with interleukin-1-beta developed greater ibotenate-induced brain damage than controls, an effect blocked by the co-administration of nimesulide (cyclooxygenase-2 inhibitor) or indomethacin (cyclooxygenase-1 and -2 inhibitor). nimesulide 150-160 prostaglandin-endoperoxide synthase 1 Mus musculus 207-230